{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:52:44Z","timestamp":1773280364640,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T00:00:00Z","timestamp":1537747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim was to assess the influence of corticosteroid therapy (<jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content>) on orthodontic tooth movement (<jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content>). A narrative review of studies performed in animal models. Indexed databases were searched up to and including May 2018 to address the following focused question: \u201cDoes <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> affect <jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content>?\u201d The following eligibility criteria were imposed: (a) original studies; (b) presence of a control group (<jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content> without <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content>); (c) intervention: effect of <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content>; and (d) statistical analysis. Quality assessment was performed using the Animal Research Reporting In Vivo Experiment (<jats:styled-content style=\"fixed-case\">ARRIVE<\/jats:styled-content>) guidelines. Case series, case reports, commentaries, historic reviews and letters to the Editor were excluded. Ten studies performed on animal models were included. The experimental duration ranged between 3 and 49\u00a0days. Two studies reported that <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> decreases the magnitude of <jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content>, two studies showed no significant influence of <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content>, and two studies found that <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> increases <jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content>. Two studies reported <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> significantly decreases bone density and increases bone resorption during <jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content>. In one study, <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> significantly decreased orthodontically induced root resorption. The minimum, median and highest scores (out of 20) based on <jats:styled-content style=\"fixed-case\">ARRIVE<\/jats:styled-content> guidelines were 7, 15.5 and 18, respectively. The influence of <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> on <jats:styled-content style=\"fixed-case\">OTM<\/jats:styled-content> in animal models remains debatable.<\/jats:p>","DOI":"10.1111\/ocr.12243","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T05:53:47Z","timestamp":1537854827000},"page":"216-224","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Influence of corticosteroid therapy on orthodontic tooth movement: A narrative review of studies in animal\u2010models"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5356-4406","authenticated-orcid":false,"given":"Dimitrios","family":"Michelogiannakis","sequence":"first","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics Eastman Institute for Oral Health University of Rochester  Rochester NY, USA"},{"name":"Department of Community Dentistry and Oral Disease Prevention Eastman Institute for Oral Health University of Rochester  Rochester NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deema","family":"Al\u2010Shammery","sequence":"additional","affiliation":[{"name":"Department of Orthodontics College of Dentistry Riyadh Elm University  Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Emile","family":"Rossouw","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics Eastman Institute for Oral Health University of Rochester  Rochester NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hameeda Bashir","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Private Dental Practice  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohaib","family":"Akram","sequence":"additional","affiliation":[{"name":"Department of Periodontology Ziauddin University  Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios E.","family":"Romanos","sequence":"additional","affiliation":[{"name":"Oral Surgery and Implant Dentistry Dental School Johann Wolfgang Goethe University of Frankfurt  Frankfurt Germany"},{"name":"Department of Periodontology Stony Brook University  Stony Brook NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9253-1989","authenticated-orcid":false,"given":"Fawad","family":"Javed","sequence":"additional","affiliation":[{"name":"Department of Periodontology Stony Brook University  Stony Brook NY, USA"},{"name":"Department of General Dentistry Eastman Institute for Oral Health University of Rochester  Rochester NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2014.07.007"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2013.10.022"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(18)30184-X"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S145221"},{"key":"e_1_2_8_6_1","first-page":"Cd007606","article-title":"Glucocorticosteroid\u2010free versus glucocorticosteroid\u2010containing immunosuppression for liver transplanted patients","volume":"4","author":"Fairfield C","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.240560304"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0889-5406(92)70046-D"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-6343.2004.00278.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2945"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.17796\/jcpd.38.3.n04h7105121663t6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(72)90133-9"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjq173"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12137"},{"key":"e_1_2_8_16_1","first-page":"118","article-title":"Orthodontic tooth movement in the prednisolone\u2010treated rat","volume":"70","author":"Ong CK","year":"2000","journal-title":"Angle Orthod"},{"key":"e_1_2_8_17_1","first-page":"486","article-title":"Growth hormone receptor and IGF\u2010I receptor immunoreactivity during orthodontic tooth movement in the prednisolone\u2010treated rat","volume":"71","author":"Ong CK","year":"2001","journal-title":"Angle Orthod"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-6343.2006.00342.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/19.1.21"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-43"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.00872.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2005.04.005"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/26.5.483"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12175"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-500X.119726"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098856"}],"container-title":["Orthodontics &amp; 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