{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T03:18:30Z","timestamp":1792898310311,"version":"4.5.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,6,28]],"date-time":"2020-06-28T00:00:00Z","timestamp":1593302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The literature is scarce on studies comparing secondary alveolar bone graft (SABG) performed early at approximately 5\u20106\u00a0years and at the conventional time at 9\u201011\u00a0years.\u00a0This systematic literature review(SLR) aimed to compare clinical outcomes after two different timings of SABG in children with unilateral and bilateral cleft lip and palate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The inclusion criteria were\u00a0autogenous iliac grafts\u00a0and the following study designs:\u00a0case control, cohort, clinical controlled trial (CCT), randomized CCT (RCCT), and previous SLRs. Ovid MEDLINE, Ovid EMBASE, Web of Science, Scopus, Cochrane, ProQuest and Google Scholar were the primary databases. Two calibrated examiners worked independently to select the articles. The MINORS evaluation method for surgical non\u2010RCTs was used to assess for quality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>1,111 articles were retrieved and 19 qualified. Different clinical and radiographic outcomes such as bone level, periodontal status, canine eruption and cleft\u2010side tooth survival were evaluated by different assessment methods such as CBCT volume, computed tomography, periodontal evaluation, panoramic, intraoral radiographs, and Bergland scale. No RCCT or meta\u2010analysis was found. None of the studies received the ideal score, which is 16 for non\u2010comparison studies and 24 for comparison studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Methodological variation, lack of standardization for initial cleft dimension and low\u2010quality level rendered a fair comparison unfeasible. Although further studies are necessary, it can be assumed that early SABG also can be an acceptable option, but this was based on a single study with a reasonable level of evidence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12394","type":"journal-article","created":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T22:34:25Z","timestamp":1590273265000},"page":"385-397","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Comparison of early and conventional autogenous secondary alveolar bone graft in children with cleft lip and palate: A systematic review"],"prefix":"10.1111","volume":"23","author":[{"given":"Fabio Henrique de Sa Leitao","family":"Pinheiro","sequence":"first","affiliation":[{"name":"Division of Orthodontics Department of Preventive Dental Science Faculty of Dentistry University of Manitoba  Winnipeg MB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert John","family":"Drummond","sequence":"additional","affiliation":[{"name":"Division of Orthodontics Department of Preventive Dental Science Faculty of Dentistry University of Manitoba  Winnipeg MB Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Martins","family":"Frota","sequence":"additional","affiliation":[{"name":"Division of Orthodontics, Hospital for Rehabilitation of Craniofacial Anomalies University of Sao Paulo  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8478-2078","authenticated-orcid":false,"given":"Theodosia N.","family":"Bartzela","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Orthopedics and Pediatric Dentistry Charit\u00e9 \u2010 Universit\u00e4tsmedizin Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3308-6376","authenticated-orcid":false,"given":"Patricia Bittencourt","family":"dos Santos","sequence":"additional","affiliation":[{"name":"State University of Rio Grande do Norte  Caico Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1597\/09-217"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-83242007000400006"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-83242004000200007"},{"issue":"3","key":"e_1_2_6_5_1","first-page":"251","article-title":"A proposed modification for the classification on cleft lip and cleft palate","volume":"10","author":"Spina V","year":"1973","journal-title":"Cleft Palate J"},{"issue":"4","key":"e_1_2_6_6_1","first-page":"471","article-title":"Maxillary arch dimensions in normal and unilateral cleft palate subjects","volume":"6","author":"Huddart A","year":"1969","journal-title":"Cleft Palate J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2003)040<0343:DABGQA>2.0.CO;2"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjr074"},{"key":"e_1_2_6_9_1","volume-title":"Early treatment of cleft lip and palate: proceedings of the third international symposium, September 27\u201029, 1984, University of Z\u00fcrich, Switzerland","author":"Hotz M","year":"1986"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1054\/jcms.2001.0217"},{"key":"e_1_2_6_11_1","volume-title":"Technik und Ergebnisse der Spaltplastiken (Technique and results of plastic operations on clefts)","author":"Axhausen G","year":"1952"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844318109103425"},{"issue":"3","key":"e_1_2_6_13_1","first-page":"175","article-title":"Elimination of the residual alveolar cleft by secondary bone grafting and subsequent orthodontic treatment","volume":"23","author":"Bergland O","year":"1986","journal-title":"Cleft Palate J"},{"issue":"2","key":"e_1_2_6_14_1","first-page":"87","article-title":"Secondary bone grafting of residual alveolar and palatal clefts","volume":"30","author":"Boyne PJ","year":"1972","journal-title":"J Oral Surg"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1055665617738401"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(76)90258-X"},{"key":"e_1_2_6_17_1","first-page":"326","volume-title":"Management of Cleft Lip and Palate","author":"Watson ACHSD","year":"2004"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-0358.57200"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/1055665618792791"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1201\/9780429258589"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2007.12.010"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2015.09.003"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1597\/15-030"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000001766"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2017.04.003"},{"issue":"2","key":"e_1_2_6_26_1","first-page":"126","article-title":"Repair of alveolar cleft defects with autogenous bone grafting: periodontal evaluation","volume":"23","author":"Eldeeb ME","year":"1986","journal-title":"Cleft Palate J"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(87)90439-3"},{"issue":"3","key":"e_1_2_6_28_1","first-page":"82","article-title":"Bone transplantation in cleft palate patients. A retrospective study","volume":"106","author":"Maningky M","year":"1999","journal-title":"Ned Tijdschr Tandheelkunde"},{"issue":"3","key":"e_1_2_6_29_1","first-page":"400","article-title":"Evaluation of the effects of secondary alveolar bone grafting in both adults and children with cleft lip and palate","volume":"17","author":"Loh S","year":"1988","journal-title":"Ann Acad Med Singapore"},{"key":"e_1_2_6_30_1","first-page":"61","article-title":"Clinical results of secondary osteoplasty of maxillary clefts in mixed dentition with lip\u2010maxillary\u2010palatal clefts","volume":"38","author":"Horch H","year":"1993","journal-title":"Fortschr Kiefer Gesichts\u2010Chir"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(03)00361-8"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2005.11.005"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1597\/06-047.1"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/20.2.115"},{"issue":"1","key":"e_1_2_6_35_1","first-page":"49","article-title":"A retrospective study of bilateral alveolar bone grafting","volume":"15","author":"Mao C","year":"2000","journal-title":"Chin Med Sci J"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2001.115274"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2012.04.015"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/scs.0b013e31814e059b"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1597\/06-054"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000100"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02748.x"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1051\/orthodfr\/2017011"},{"key":"e_1_2_6_43_1","unstructured":"Oxford Centre for Evidence\u2010based Medicine \u2013 Levels of Evidence.Centre for Evidence\u2010Based Medicine.2009.https:\/\/www.cebm.net\/2009\/06\/oxford-centre-evidence-based-medicine-levels-evidence-march-2009\/. Accessed August 9 2019"}],"container-title":["Orthodontics &amp; Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Focr.12394","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ocr.12394","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ocr.12394","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ocr.12394","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T07:40:27Z","timestamp":1693813227000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ocr.12394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,28]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/ocr.12394"],"URL":"https:\/\/doi.org\/10.1111\/ocr.12394","archive":["Portico"],"relation":{},"ISSN":["1601-6335","1601-6343"],"issn-type":[{"value":"1601-6335","type":"print"},{"value":"1601-6343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,28]]},"assertion":[{"value":"2020-03-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}