{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:01:50Z","timestamp":1785207710482,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T00:00:00Z","timestamp":1623888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the outcome of secondary alveolar bone grafting (SABG) in a series of consecutive patients with clefts involving the alveolus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and Setting<\/jats:title><jats:p>Retrospective cohort study of consecutive operations performed between June 2011 and September 2016 by a single surgeon at a single United Kingdom cleft center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 160 patients with a cleft\/s involving the alveolus, inclusive of syndromic patients and those with atypical facial clefts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>A standard protocol involved an oral hygiene program, pre\u2010surgical orthodontics where necessary and autologous bone grafting from the iliac crest.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measure(s)<\/jats:title><jats:p>The Kindelan bone\u2010fill index was used to evaluate success using occlusal radiographs. Weighted Cohen's kappa coefficient was used as a measure of intra\u2010 and inter\u2010rater agreement. Fisher's exact test was used to examine the effects of type of cleft, pre\u2010surgical orthodontics or age at time of SABG on radiographic outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 200 SABGs assessed. Mean age at time of SABG was 9.1\u00a0years old (SD 1.1) with 99% (n\u00a0=\u00a0198) of grafts deemed successful. There were two failures where re\u2010graft was performed successfully during the study period. A grade 1 outcome was achieved for 92.5% (n\u00a0=\u00a0185) of grafts and this did not appear to be affected by type of cleft (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.290), pre\u2010surgical orthodontics (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.380) or age at time of SABG (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.081).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The high success rate reported in this study supports the favorable outcomes of a high\u2010volume cleft surgeon. These findings can be used for comparative audit with similar units providing cleft care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12508","type":"journal-article","created":{"date-parts":[[2021,6,8]],"date-time":"2021-06-08T21:59:53Z","timestamp":1623189593000},"page":"128-133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Radiographic outcome of secondary alveolar bone grafting in patients with alveolar clefts"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1096-5012","authenticated-orcid":false,"given":"Daniel","family":"Stonehouse\u2010Smith","sequence":"first","affiliation":[{"name":"Cleft Lip and Palate Unit Royal Manchester Children\u2019s Hospital  Manchester UK"},{"name":"Department of Orthodontics Guy\u2019s and St Thomas\u2019 NHS Foundation Trust  London 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