{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:35:08Z","timestamp":1767983708577,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T00:00:00Z","timestamp":1639958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The study aimed to investigate the effects of hypodontia on the sagittal and vertical dimensions of the jaws, dentition and the related soft tissue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The hypodontia group included 111 patients whose growth was completed with one or more congenitally missing teeth (CMT). Sixty additional patients with skeletal and dental class I relationship, without CMT, and who completed growth, were included as the control group. The hypodontia group was divided into three subgroups according to the intermaxillary (maxillary or mandibular) location, intramaxillary (anterior or posterior) location and the severity of hypodontia (mild: 1\u20102 CMT or moderate: 3\u20106 CMT). Twenty\u2010three measurements were performed on lateral cephalograms of the patients. The one\u2010way and Kruskal\u2010Wallis Analysis of Variance tests were used for the statistical analysis. The false discovery\u2010rate analysis was applied for the multiple comparison adjustment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant difference was found in the skeletal measurements between all hypodontia subgroups and the control (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a0.05). Upper incisors were found to be retroclined in the anterior hypodontia group. The upper lip was found to be protruded in the mandibulary hypodontia group compared to the control (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The mild\u2010to\u2010moderate hypodontia did not produce a significant skeletal effect. However, hypodontia can affect the incisors, especially when CMT is in the anterior region. Besides, the effects of severe hypodontia could not be evaluated due to the insufficient number of oligodontia patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12550","type":"journal-article","created":{"date-parts":[[2021,11,27]],"date-time":"2021-11-27T13:27:36Z","timestamp":1638019656000},"page":"409-415","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of the effects of hypodontia on the morphology of craniofacial structures"],"prefix":"10.1111","volume":"25","author":[{"given":"Zeynep Aybike","family":"Yelmer","sequence":"first","affiliation":[{"name":"Department of Orthodontics Tokat Gaziosmanpasa University Faculty of Dentistry  Tokat Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3007-1179","authenticated-orcid":false,"given":"Sibel","family":"Akbulut","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Tokat Gaziosmanpasa University Faculty of Dentistry  Tokat Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature06153"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(99)00322-6"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9378325"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1698333"},{"key":"e_1_2_10_6_1","first-page":"258","article-title":"Reported prevalence of congenitally missing teeth in two Norwegian counties","volume":"19","author":"Nordgarden H","year":"2002","journal-title":"Community Dent Health"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910808700715"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.117.2.461"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0494-348"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-160X-7-23"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2016.03.021"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(03)00620-6"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2008.09.002"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8644(200002)111:2<177::AID-AJPA4>3.0.CO;2-8"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/16.2.104"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.2319\/082905-303"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-004-0034-5"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjn111"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.2319\/091012-722.1"},{"key":"e_1_2_10_20_1","first-page":"61","article-title":"Timing of interceptive orthodontic measures based on stages of maturation","author":"Bjork A","year":"1972","journal-title":"Trans Eur Orthod Soc"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(95)70157-5"},{"key":"e_1_2_10_22_1","first-page":"358","article-title":"Statistical methods for medical and biological students","volume":"14","author":"Dahlberg G","year":"1940","journal-title":"Br Med J"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/93.3.491"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(69)90034-7"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/103503"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2015.05.024"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1067\/mod.2002.123948"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.2319\/0003-3219(2008)078[0591:CBCACV]2.0.CO;2"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(95)70047-1"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.2319\/072309-411.1"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016358209041117"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/19.1.71"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2004.00158.x"}],"container-title":["Orthodontics &amp; 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