{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T02:00:43Z","timestamp":1775786443202,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to investigate associations between alveolar bone height changes on the labial and lingual sides in mandibular incisors and three\u2010dimensional orthodontic tooth movement, involving apex displacement, tooth inclination, and angulation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>The samples consisted of 43 adult patients treated with Invisalign aligners. All subjects were skeletal Class I patients without extraction in mandible. Pre\u2010treatment and post\u2010treatment cone\u2010beam computed tomographic images were obtained to measure labial and lingual alveolar bone height and bone thickness at apex level in four mandibular incisors. An x, y, z coordinate system, superimposing on mandibular body, was established to analyse three\u2010dimensional apex movement and tooth inclination and angulation changes. Multiple linear regression was applied to identify the determining factors of marginal bone changes during orthodontic treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three directions of apex movement (anteroposterior, vertical, transverse) significantly associated with alveolar bone height changes. Inclination changes had a strong effect on lingual marginal bone, while tooth angulation had no significant effect on alveolar bone height. Incisors with lingual bodily movement were more susceptible to lingual marginal bone recession compared with lingual tipping movement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Alveolar bone height changes on the labial and lingual sides were associated with three\u2010dimensional apex movement, inclination changes, and movement patterns. Appropriate tooth movement should be considered to avoid excessive marginal bone loss around mandibular incisors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12583","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T09:18:30Z","timestamp":1651483110000},"page":"91-99","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Association between alveolar bone height changes in mandibular incisors and three\u2010dimensional tooth movement in non\u2010extraction orthodontic treatment with Invisalign"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3314-3705","authenticated-orcid":false,"given":"Yishan","family":"Zhang","sequence":"first","affiliation":[{"name":"The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei\u2010MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology Wuhan University  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei\u2010MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology Wuhan University  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6]]},"reference":[{"issue":"2","key":"e_1_2_12_2_1","first-page":"95","article-title":"The anterior alveolus: its importance in limiting orthodontic treatment and its influence on the occurrence of iatrogenic sequelae","volume":"66","author":"Handelman CS","year":"1996","journal-title":"Angle Orthod"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(96)80006-0"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2012.00964.x"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.2319\/041419-266.1"},{"issue":"3","key":"e_1_2_12_6_1","first-page":"238","article-title":"Correlation between mandibular central incisor Proclination and gingival recession during fixed appliance therapy","volume":"72","author":"Djeu G","year":"2002","journal-title":"Angle Orthod"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cju073"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.2319\/021414-110.1"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.5051\/jpis.2020.50.3.146"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.2319\/081711-526.1"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0889-5406(90)70115-S"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2015.07.034"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2011.06.021"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sodo.2015.07.007"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.4041\/kjod.2019.49.2.97"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520982708"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.2319\/080219-510.1"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.2319\/040815-235.1"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4158.358-b"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.5624\/isd.20200260"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.2319\/111820-943.1"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2019.10.017"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjz039"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2015.05.026"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.2319\/063019-443.1"},{"issue":"8","key":"e_1_2_12_26_1","first-page":"12866","article-title":"Presurgical orthodontic decompensation alters alveolar bone condition around mandibular incisors in adults with skeletal class III malocclusion","volume":"8","author":"Sun B","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.2319\/070111-424.1"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb00954.x"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.2319\/101415-686.1"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2003.12.026"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2006.01.015"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12343"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1179\/bjo.13.1.33"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2012.03.028"}],"container-title":["Orthodontics &amp; Craniofacial Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ocr.12583","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ocr.12583","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ocr.12583","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T16:09:35Z","timestamp":1692547775000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ocr.12583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/ocr.12583"],"URL":"https:\/\/doi.org\/10.1111\/ocr.12583","archive":["Portico"],"relation":{},"ISSN":["1601-6335","1601-6343"],"issn-type":[{"value":"1601-6335","type":"print"},{"value":"1601-6343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"2021-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}