{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T06:27:01Z","timestamp":1763706421889,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,10,30]],"date-time":"2022-10-30T00:00:00Z","timestamp":1667088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mixed dentition determines an important period of occlusion development in childhood.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to evaluate the aesthetic impact of the midline diastema cut\u2010off point in mixed dentition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A cross\u2010sectional study was performed with 257 children aged 8\u201010\u2009years in late mixed dentition, with midline diastema of 1\u20105\u2009mm and normal maxillary overjet. Orthodontic Aesthetic Subjective Impact Score determined the aesthetic impact of the midline diastema. Four quartiles of diastema measurements and impact scores were considered as cut\u2010off points. Receiver Operating Characteristic curves were constructed, and the distances representing the distances to the ideal point were calculated. The Yuden index determined the efficiency of measuring the diastema to assess the aesthetic impact. The Kruskal\u2010Wallis test compared the groups of participants classified according to the diastema cut\u2010off by the sample quartile regarding the impact score. The analyses were performed with a significance level of 5%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference between the four groups of measurement quartiles of the diastema regarding the aesthetic impact (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The perception of dental aesthetics in mixed dentition children was not affected by the midline diastema, regardless of the cut\u2010off point.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12613","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T14:28:03Z","timestamp":1665757683000},"page":"331-337","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Should midline diastema in mixed dentition be an aesthetic concern?"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4813-2152","authenticated-orcid":false,"given":"Carlos Vinicius da Silva","family":"Ara\u00fajo","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Araras Dental School University Center of Herm\u00ednio Ometto Foundation\u2010FHO  Araras S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8875-8611","authenticated-orcid":false,"given":"Carolina Carmo","family":"de Menezes","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Araras Dental School University Center of Herm\u00ednio Ometto Foundation\u2010FHO  Araras S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3490-5030","authenticated-orcid":false,"given":"Milton","family":"Santamaria\u2010Jr","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Araras Dental School University Center of Herm\u00ednio Ometto Foundation\u2010FHO  Araras S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2673-3627","authenticated-orcid":false,"given":"Marcelo de Castro","family":"Meneghim","sequence":"additional","affiliation":[{"name":"Department of Health Sciences and Child Dentistry, Piracicaba Dental School UNICAMP  Piracicaba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7203-2867","authenticated-orcid":false,"given":"Silvia\u00a0Am\u00e9lia\u00a0Scudeler","family":"Vedovello","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Araras Dental School University Center of Herm\u00ednio Ometto Foundation\u2010FHO  Araras S\u00e3o Paulo Brazil"},{"name":"Department of Health Sciences and Child Dentistry, Piracicaba Dental School UNICAMP  Piracicaba S\u00e3o Paulo 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