{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:53:17Z","timestamp":1780617197886,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe a method to calculate the total intra\u2010articular volume (inter\u2010osseous space) of the temporomandibular joint (TMJ) determined by cone\u2010beam computed tomography (CBCT). This could be used as a marker of tissue proliferation and different degrees of soft tissue hyperplasia in juvenile idiopathic arthritis (JIA) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Axial single\u2010slice CBCT images of cross\u2010sections of the TMJs of 11 JIA patients and 11 controls were employed. From the top of the glenoid fossa, in the caudal direction, an average of 26 slices were defined in each joint (<jats:italic>N<\/jats:italic>\u2009=\u200944). The interosseous space was manually delimited from each slice by using dedicated software that includes a graphic interface. TMJ volumes were calculated by adding the areas measured in each slice. Two volumes were defined: <jats:italic>V<\/jats:italic><jats:sub><jats:italic>e<\/jats:italic>\u2212<jats:italic>i<\/jats:italic><\/jats:sub> and <jats:italic>V<\/jats:italic><jats:sub><jats:italic>i<\/jats:italic><\/jats:sub>, where <jats:italic>V<\/jats:italic><jats:sub><jats:italic>e<\/jats:italic>\u2212<jats:italic>i<\/jats:italic><\/jats:sub> is the inter\u2010osseous space, volume defined by the borders of the fossa and <jats:italic>V<\/jats:italic><jats:sub><jats:italic>i<\/jats:italic><\/jats:sub> is the internal volume defined by the condyle. An intra\u2010articular volume filling index (IF) was defined as <jats:italic>V<\/jats:italic><jats:sub><jats:italic>e<\/jats:italic>\u2212<jats:italic>i<\/jats:italic><\/jats:sub>\/<jats:italic>V<\/jats:italic><jats:sub><jats:italic>i<\/jats:italic><\/jats:sub>, which represents the filling of the space.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The measured space of the intra\u2010articular volume, corresponding to the intra\u2010articular soft tissue and synovial fluid, was more than twice as large in the JIA group as in the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presented method, based on CBCT, is feasible for assessing inter\u2010osseus joint volume of the TMJ and delimits a threshold of intra\u2010articular changes related to intra\u2010articular soft tissue proliferation, based on differences in volumes. Intra\u2010articular soft tissue is found to be enlarged in JIA patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12702","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T07:20:32Z","timestamp":1690874432000},"page":"203-210","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Quantification of temporomandibular joint space in patients with juvenile idiopathic arthritis assessed by cone beam computerized tomography"],"prefix":"10.1111","volume":"27","author":[{"given":"Mar\u00eda Florinda","family":"Otero","sequence":"first","affiliation":[{"name":"Health Research Institute of Santiago de Compostela (IDIS)  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo G.","family":"Tahoces","sequence":"additional","affiliation":[{"name":"Departamento de Electr\u00f3nica e Computaci\u00f3n Universidade de Santiago de Compostela  Santiago de 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