{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:08:33Z","timestamp":1790633313933,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:00Z","timestamp":1696032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study is to evaluate the maxillary sinus (MS) volume and pathologies, nasal septum (NS) deviation, and MS septa formation in children with and without cleft lip and palate (CLP); also to investigate the possible causes of MS pathologies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Cone Beam Computed Tomography (CBCT) images of 200 (100 CLP, 100 control) children (5\u201318\u2009years old) were evaluated from the computer database of <jats:italic>Marmara University Faculty of Dentistry<\/jats:italic>. Children with a history of maxillofacial trauma, diseases that affect bone metabolism, orthognathic surgery, extrinsic pathologies of the MS, and accompanying syndromes were excluded. NS deviation, MS septa formation, volume, and pathologies evaluated using Mimics\u00ae software. In statistical evaluations; Student <jats:italic>t<\/jats:italic> test, paired sample <jats:italic>t<\/jats:italic> test, Chi\u2010Square test, Fisher's Exact Chi\u2010Square test, Continuity Correction, Chi\u2010square analysis in one\u2010eyed layout, McNemar test, and logistic regression analysis were used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Total MS volume was smaller in the CLP group (21\u2009232\u2009mm<jats:sup>3<\/jats:sup>) than in control children (23\u2009763\u2009mm<jats:sup>3<\/jats:sup>) (<jats:italic>P<\/jats:italic>:0.026). NS deviation and MS pathology were more frequent in the CLP. In logistic regression analysis, there was no significant relation between the presence of NS deviation and pathology in MS. The presence of CLP increased the risk of MS pathology by 2.6 times.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found that children with CLP have less MS volume and an increased rate of NS deviation and MS pathology compared to the control group. Further radiological and clinical studies are needed to explain the predisposing factors of MS pathology in children with CLP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12718","type":"journal-article","created":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T07:10:20Z","timestamp":1696057820000},"page":"27-34","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of maxillary sinus volumes and pathologies in children with and without cleft lip and palate using cone beam computed tomography"],"prefix":"10.1111","volume":"27","author":[{"given":"Busra Dilara","family":"Altun","sequence":"first","affiliation":[{"name":"Faculty of Dentistry, Department of Oral and Maxillofacial Radiology Marmara University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asim","family":"Dumlu","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Department of Oral and 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