{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:27:05Z","timestamp":1793298425736,"version":"4.5.0"},"reference-count":40,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Investigate associations between cleft laterality in patients with non\u2010syndromic unilateral cleft lip and palate (UCLP) and oral\u2010health, dental\u2010arch, speech, audiological, psychological and nasolabial\u2010aesthetic outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Secondary data analysis of the outcomes of 5\u2010year\u2010old children with non\u2010syndromic complete UCLP identified from three studies: Cleft Collective (n\u2009=\u2009155), Cleft Care UK (CCUK) (n\u2009=\u2009266) and Clinical Standards Advisory Group (CSAG) study (n\u2009=\u2009238). Outcome measures included occlusal assessment using the 5\u2010year\u2010old's index score, speech intelligibility rating using the CAPS\u2010A Audit tool, audiological assessment using pure tone audiometry, nasolabial aesthetic assessment using the Asher\u2010McDade tool, oral\u2010health assessment using decayed, missing, filled teeth scores and parent\u2010reported outcomes. Logistic regression with adjustment for age, sex and index\u2010of\u2010multiple\u2010deprivation scores were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No differences were found in patient\u2010reported outcomes between the left and right clefts in the Cleft Collective study. From the CCUK study, right clefts had poorer speech (n\u2009=\u2009236; 95% CI 1.09, 3.42; and <jats:italic>P<\/jats:italic>\u2009=\u2009.03) and hearing outcomes (n\u2009=\u2009211; 95% CI 1.03, 3.43; <jats:italic>P<\/jats:italic>\u2009=\u2009.04). In the CSAG study, patients with left clefts were more likely to be teased (n\u2009=\u2009213; 95% CI 0.26, 0.85; and <jats:italic>P<\/jats:italic>\u2009=\u2009.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Weak associations between cleft laterality, speech, hearing and psychological outcomes were found, however the findings were inconsistent across the studies. This study contributes to evidence of associations between laterality and outcomes in children born with UCLP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12747","type":"journal-article","created":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T09:13:10Z","timestamp":1704791590000},"page":"49-61","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Should left\u2010 and right\u2010sided unilateral cleft lip and palate patients be grouped together when reporting the outcomes?"],"prefix":"10.1111","volume":"27","author":[{"given":"Manar","family":"Al\u2010Hassani","sequence":"first","affiliation":[{"name":"University of Bristol  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Fowler","sequence":"additional","affiliation":[{"name":"University of Bristol  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Wren","sequence":"additional","affiliation":[{"name":"University of Bristol  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Leary","sequence":"additional","affiliation":[{"name":"University of Bristol  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Davies","sequence":"additional","affiliation":[{"name":"University of Bristol  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1055665620951099"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/gepi.22420"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1101\/2021.08.04.21261594v1"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000008277"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000008769"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/10556656221089160"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2010.123"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-046944"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-2662"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.38567"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/10556656211028506"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2016.05.006"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1999_036_0527_aolvru_2.3.co_2"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1992_029_0413_asciso_2.3.co_2"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1997_034_0242_anifas_2.3.co_2"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1994_031_0372_dfitfy_2.3.co_2"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12104"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ortho\/25.1.21"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1597\/14-306"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2001_038_0038_clapci_2.0.co_2"},{"key":"e_1_2_12_22_1","unstructured":"GOV.UK.The English Index of Multiple Deprivation (IMD) 2015\u2010Guidance.2015.https:\/\/www.gov.uk\/government\/statistics\/english\u2010indices\u2010of\u2010deprivation\u20102015"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2001_038_0020_clapci_2.0.co_2"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1597\/04-141.1"},{"key":"e_1_2_12_25_1","article-title":"Pure tone air and bone conduction threshold audiometry with and without masking \u2010 British Society of Audiology","author":"BSA","year":"2018","journal-title":"Br Soc Audiol"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1991_028_0385_doamfr_2.3.co_2"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1226(97)91275-3"},{"key":"e_1_2_12_28_1","unstructured":"MedinaJ ButterworthS FitzsimonsKJ RussellC WahedallyH van derMeulenJ.CRANE database 2022 annual report \u2013 CRANE database. 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