{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T18:22:54Z","timestamp":1783362174009,"version":"3.54.6"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T00:00:00Z","timestamp":1705017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Previous studies have shown unilateral posterior crossbite is associated with mandibular asymmetry in morphology and position. However, it remains unclear whether unilateral Brodie bite plays a similar role in mandibular development. Therefore, this study aims to investigate the morphological and positional symmetry of mandibles in patients with unilateral Brodie bite by three\u2010dimensional anaylsis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fourteen patients with unilateral Brodie bite (mean age 18.43 \u00b1 4.24 years) and fourteen sex\u2010 and age\u2010matched patients with normal occlusion (mean age 18.07 \u00b1 5.48 years) underwent cone\u2010beam computed tomography (CBCT) scans. 3D surface mesh models of their mandibles were established using Mimics Research 19.0. The surface matching percentage was compared between the original and mirrored mandible by Geomagic Control X software. Furthermore, the dimension and position of the temporomandibular joint (TMJ) were determined for both groups using InVivoDental 5.0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For surface\u2010to\u2010surface deviation analysis, the percentage of mismatch in patients with unilateral Brodie bite was significantly higher than the control group at \u00b10.50\u2009mm, \u00b10.75\u2009mm, and\u2009\u00b11.00\u2009mm tolerance (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). In patients with unilateral Brodie syndrome, the condyles on the scissors\u2010bite side showed a significantly more anterior position (<jats:italic>P<\/jats:italic>\u2009=\u2009.03), greater medial inclination (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), and larger posterior TMJ space (<jats:italic>P<\/jats:italic>\u2009=\u2009.01) than the non\u2010scissors\u2010bite side.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with unilateral Brodie bite exhibit a more asymmetrical mandibular morphology, with a greater anterior condylar position and posterior joint space on the scissors\u2010bite side, indicating that early diagnosis and treatment may be necessary for patients with unilateral Brodie bite.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12755","type":"journal-article","created":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T07:16:56Z","timestamp":1705130216000},"page":"474-484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Three\u2010dimensional analysis of mandibular morphology asymmetry and temporomandibular joint position in patients with unilateral Brodie bite"],"prefix":"10.1111","volume":"27","author":[{"given":"J.","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Prosthodontics and Orthodontics, Center of Stomatology, Xiangya Hospital Central South University  Changsha Hunan China"},{"name":"Department of Orthodontics, Hospital of Stomatology Sun Yat\u2010sen University  Guangzhou Guangdong China"},{"name":"Guanghua School of Stomatology Sun Yat\u2010sen University  Guangzhou Guangdong 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