{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:18:53Z","timestamp":1787015933250,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The present study aims to quantitatively assess secondary alveolar bone graft (SABG) resorption in unilateral cleft lip, alveolus and palate (UCLAP) patients in a 2\u20133\u2009year longitudinal follow\u2010up setting by using a validated 3D protocol. Furthermore, the potential relation of SABG resorption with maxillary canine position and a number of patient\u2010related factors was investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>UCLAP patients who underwent SABG and had good quality CBCT images at the following timepoints were included in the study: pre\u2010operative (T0), immediate (T1), 6\u2009months (T2) and either 1\u20132\u2009years (T3) or 2\u20133\u2009years (T4) post\u2010operative. The final bone grafted region was defined on the T1 scans and refined in the registered T0 scans. The bone graft after resorption was determined by applying threshold\u2010based segmentation on the registered T2, T3 or T4 scans within the segmented bone graft volume. The position of the canines was determined at every timepoint at the cleft and non\u2010cleft side.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010five UCLAP patients (mean age 9.0\u2009\u00b1\u20091.3\u2009years) were included. In the first 6\u2009months after SABG, 43.6% bone resorption was recorded. 2\u20133\u2009years post\u2010operative, 56% bone resorption was found if the maxillary canine was not yet erupted and 42.7% if it erupted through the graft. The vertical position of the canines was significantly higher on the cleft side at T3.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The present study reports significant SABG resorption over time. However, no correlation was found between SABG resorption and canine position, nor between other patient\u2010related factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ocr.12763","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T09:33:48Z","timestamp":1706780028000},"page":"100-108","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Three\u2010dimensional evaluation of secondary alveolar bone grafting in patients with unilateral cleft lip and palate: A 2\u20133\u2009year post\u2010operative follow\u2010up"],"prefix":"10.1111","volume":"27","author":[{"given":"Kaat","family":"Doucet","sequence":"first","affiliation":[{"name":"Department of Oral Health Sciences\u2010Orthodontics, KU Leuven and Dentistry University Hospitals Leuven  Leuven 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