{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T18:02:20Z","timestamp":1780941740652,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study assessed overall quality of life (QoL) over time in youth with cleft lip and palate (CLP) undergoing maxillary protraction treatment or orthognathic surgery for class III malocclusion to identify any differences in QoL based on treatment group and outcome success.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A prospective longitudinal cohort study was conducted in two pediatric hospitals. The Short Form Health Survey (SF\u201012) measured physical and mental QoL prior to treatment, at maximal correction, at treatment completion, and at 1\u2010year post treatment. Analyses included one\u2010sample, two\u2010sample, and paired t\u2010tests and analyses of variance and covariance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participants (N\u2009=\u200991) either completed protraction (n\u2009=\u200953) at age 11\u201314 or surgery (n\u2009=\u200938) at age 16\u201321. Participants were mostly Latinx (67%) males (55%) born with unilateral CLP (81%) and there were no demographic differences between the two groups other than age. The total sample's QoL was in the average range and significantly higher than national norms. No significant differences were found in QoL\u2010based outcome success; however, the protraction group showed a gradual physical QoL improvement over time, while the surgery group experienced a temporary drop in physical QoL postoperatively. At treatment completion, higher physical QoL was associated with higher socioeconomic status. At a year post treatment, mental QoL was significantly higher for males.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both protraction and surgery appear to be acceptable treatment options in terms of overall QoL for youth with CLP. While treatment success did not impact QoL, there were some differences in physical QoL coinciding with the treatment phase as well as individual factors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ocr.12810","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T06:13:33Z","timestamp":1717136013000},"page":"813-820","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of protraction or orthognathic surgery for class <scp>III<\/scp> malocclusion on longitudinal quality of life in patients with cleft lip and palate"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6618-732X","authenticated-orcid":false,"given":"Bocheng","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical and Health Economics, School of Pharmacy University of Southern California  Los Angeles California 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