{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T22:07:46Z","timestamp":1788386866915,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:00:00Z","timestamp":1760054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n This study compared maxillary sinus volume (MSV) in patients with unilateral non\u2010syndromic cleft lip and palate (CLP) to a skeletally matched control group with a skeletal class III pattern (group CTR) using cone\u2010beam computed tomography (CBCT) images.<\/jats:p>\n <\/jats:sec>\n \n Materials\/Methods<\/jats:title>\n \n Ninety CBCT images were evaluated, including 45 patients with unilateral CLP (group CLP, mean age 24.3\u2009\u00b1\u20096.1) and 45 patients with Class III malocclusion (group CTR, mean age 25.3\u2009\u00b1\u20095.9). Both groups were skeletally matched based on SNA, SNB, ANB, GoGn\u2010SN angles and Wits appraisal values. MSV was measured using ITK\u2010SNAP software. The Kolmogorov\u2013Smirnov test confirmed normal data distribution. Intergroup comparisons of average MSV, MSV stratified per side, cephalometric parameters and gender differences were performed using Student's\n t<\/jats:italic>\n \u2010test. Intragroup comparisons (cleft vs. non\u2010cleft side, right vs. left side) were conducted using a paired\n t<\/jats:italic>\n \u2010test. Statistical significance was set at\n p<\/jats:italic>\n \u2009<\u20090.05.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n No statistically significant differences in average MSV were found between the CLP group (7589.74\u2009\u00b1\u20094060.23\u2009mm\n 3<\/jats:sup>\n ) and the CTR group (7901.90\u2009\u00b1\u20093667.69\u2009mm\n 3<\/jats:sup>\n ) (\n p<\/jats:italic>\n \u2009=\u20090.59). However, within the CLP group, the MSV on the cleft side (6870.53\u2009\u00b1\u20093695.29\u2009mm\n 3<\/jats:sup>\n ) was significantly smaller than on the non\u2010cleft side (8308.96\u2009\u00b1\u20094316.53\u2009mm\n 3<\/jats:sup>\n ) (\n p<\/jats:italic>\n \u2009<\u20090.05). No significant gender differences regarding MSV values were found (\n p<\/jats:italic>\n \u2009>\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Unilateral cleft lip and palate resulted in a significantly smaller MSV on the cleft side in CLP patients. However, the average MSV of CLP patients was not significantly reduced compared to non\u2010cleft patients with a skeletal Class III pattern.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ocr.70041","type":"journal-article","created":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T12:15:24Z","timestamp":1760098524000},"page":"74-82","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparative Analysis of Maxillary Sinus Volume in Patients With Cleft Lip and Palate Versus Class III Malocclusion Patients Using\n CBCT<\/scp>"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5720-116X","authenticated-orcid":false,"given":"Sara","family":"Eslami","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Center for Dentistry and Oral Medicine (Carolinum) Goethe University Frankfurt Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2009-4393","authenticated-orcid":false,"given":"Anand","family":"Marya","sequence":"additional","affiliation":[{"name":"Orthodontic department, Faculty of Dentistry University of Puthisastra Phnom Penh Cambodia"},{"name":"The City of London Dental School University of Greater Manchester Bolton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Sayahpour","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Center for Dentistry and Oral Medicine (Carolinum) Goethe University Frankfurt Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"B\u00fchling","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Center for Dentistry and Oral Medicine (Carolinum) Goethe University Frankfurt Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Kopp","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Center for Dentistry and Oral Medicine (Carolinum) Goethe University Frankfurt Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanieh","family":"Mahmoudi","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry, Tehran Medical Science Islamic Azad University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmadreza","family":"Talaeipour","sequence":"additional","affiliation":[{"name":"Maxillofacial Radiology Department, Faculty of Dentistry, Tehran Medical Science Islamic Azad University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"Harsoputranto","sequence":"additional","affiliation":[{"name":"Orthodontic department, Faculty of Dentistry University of Puthisastra Phnom Penh Cambodia"},{"name":"The City of London Dental School University of Greater Manchester Bolton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8841-0447","authenticated-orcid":false,"given":"Abdolreza","family":"Jamilian","sequence":"additional","affiliation":[{"name":"The City of London Dental School University of Greater Manchester Bolton UK"},{"name":"Orthodontic Department, Faculty of Dentistry, Tehran Medical Sciences Islamic Azad University Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-03797-z"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2018.07.006"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1989.01860280040014"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13071067"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e318267bdf3"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1982.92.2.183"},{"issue":"12","key":"e_1_2_12_8_1","first-page":"691","article-title":"Evaluation of the Anatomical Variation in the Nasal Cavity and Paranasal Sinuses of Patients With Cleft Lip and Palate Using Cone Beam Computed Tomography","volume":"117","author":"Dedeoglu N.","year":"2016","journal-title":"Bratislavsk\u00e9 Lek\u00e1rske Listy"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsc.2016.06.003"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2016.03.031"},{"issue":"4","key":"e_1_2_12_11_1","first-page":"354","article-title":"An Inquiry Into the Anatomy and Pathology of the Maxillary Sinus","volume":"44","author":"Underwood A. 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