{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T09:11:53Z","timestamp":1777972313185,"version":"3.51.4"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    To compare the extent of root resorption, assessed via three\u2010dimensional (3D) volumetric CBCT analysis, between tooth\u2010borne and bone\u2010borne rapid maxillary expansion (RME) devices. A systematic search of seven databases (PubMed, Cochrane Library, Embase, etc.) up to December 2024 identified eligible studies (randomised controlled trials, cohort studies, clinical trials) evaluating CBCT\u2010measured root resorption in patients treated with tooth\u2010borne, bone\u2010borne or hybrid RME devices. Data were analysed using STATA 17.0, employing weighted mean differences (WMDs) and random\/fixed\u2010effects models. Heterogeneity, subgroup analyses and publication bias were assessed. Sixteen studies (525 patients, 2906 teeth) were included. These studies comprised randomised controlled trials and observational studies, predominantly enrolled adolescent and young adult patients, and directly compared tooth\u2010borne and bone\u2010borne RME devices. Tooth\u2010borne RME resulted in significantly greater root resorption volume compared to bone\u2010borne devices (WMD\u2009=\u2009\u221210.4\u2009mm\n                    <jats:sup>3<\/jats:sup>\n                    , 95% CI [\u221213.9, \u22126.9], 95% prediction interval [\u221211.94, \u22128.92],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05;\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u200998.8%). Tooth\u2010borne RME also caused greater root length loss (WMD\u2009= \u22120.14\u2009mm, 95% CI [\u22120.21, \u22120.08], 95% prediction interval [\u22120.20, \u22120.08],\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05;\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u200995.6%). Tooth\u2010borne RME resulted in significantly greater root resorption volume (WMD\u2009=\u2009\u221220.7\u2009mm\n                    <jats:sup>3<\/jats:sup>\n                    ) and length (WMD\u2009=\u2009\u22120.40\u2009mm) compared to baseline, indicating increased resorption. Three\u2010dimensional CBCT analysis demonstrated superior sensitivity in detecting resorption morphology and localization compared to linear measurements. Bone\u2010borne RME devices, which are associated with reduced root resorption risks, may be related to improved force distribution to bony structures. Three\u2010dimensional volumetric CBCT assessment provides a more accurate quantification than linear measurements. Clinically, bone\u2010borne expanders are recommended for high\u2010risk patients, while tooth\u2010borne users require close CBCT monitoring. Findings should be interpreted considering limitations of the included evidence, including heterogeneity in RME devices and protocols, risk of bias in some non\u2010randomised studies, and imprecision due to limited sample sizes in subgroup analyses and lack of long\u2010term data.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration:<\/jats:bold>\n                    International Prospective Register of Systematic Reviews (PROSPERO) registration number: CRD420251018535\n                  <\/jats:p>","DOI":"10.1111\/ocr.70096","type":"journal-article","created":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T08:25:12Z","timestamp":1768638312000},"page":"506-520","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Three\u2010Dimensional Volumetric Assessment of Root Resorption in Rapid Maxillary Expansion: A Meta\u2010Analysis Comparing Tooth\u2010Borne and Bone\u2010Borne Devices"],"prefix":"10.1111","volume":"29","author":[{"given":"Chen","family":"Xue","sequence":"first","affiliation":[{"name":"Department of Stomatology Affiliated Hospital of North Sichuan Medical College  Nanchong Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianrong","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Stomatology Affiliated Hospital of North Sichuan Medical College  Nanchong Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Stomatology Affiliated Hospital of North Sichuan Medical College  Nanchong Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Qiu","sequence":"additional","affiliation":[{"name":"Medical Research Center Affiliated Hospital of North Sichuan Medical College  Nanchong Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1475-1342","authenticated-orcid":false,"given":"Lihua","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Stomatology Affiliated Hospital of North Sichuan Medical College  Nanchong Sichuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,17]]},"reference":[{"key":"e_1_2_14_2_1","first-page":"12","article-title":"The Prevalence of Malocclusion in Swedish Schoolchildren","volume":"81","author":"Thilander B.","year":"1973","journal-title":"Scandinavian Journal of Dental Research"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/26.3.237"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(82)90034-3"},{"key":"e_1_2_14_5_1","first-page":"155","article-title":"Long\u2010Term Dental Arch Changes After Rapid Maxillary Expansion Treatment: A Systematic Review","volume":"75","author":"Lagravere M. 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