{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:08:13Z","timestamp":1780463293680,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyse and compare the craniofacial characteristics of patients with nonsyndromic, surgically repaired, complete unilateral cleft lip and palate, aged 8\u201314\u2009years, treated at 10 cleft care centres.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Lateral cephalograms of 396 patients (mean age 11.2\u2009\u00b1\u20091.6\u2009years; male: female ratio 1:0.64) with unilateral cleft lip and palate from 10 comprehensive cleft care centres across India were evaluated using NemoStudio cephalometric software. Cephalograms were anonymised, coded and digitised for unbiased assessment. Two orthodontists independently traced all radiographs at different time intervals. Eleven hard\u2010tissue and seven soft\u2010tissue cephalometric variables were measured on each radiograph. Inter\u2010rater reliability was assessed using the intraclass correlation coefficient (ICC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Cephalometric analysis demonstrated statistically significant intercentre differences for sagittal skeletal and soft\u2010tissue parameters, including SNA, SNB, ANB, ANS\u2010Me\/N\u2010Me, NAPog, nasolabial angle, N\u2032A\u2032Pog\u2032 and A\u2032N\u2032B\u2032. In contrast, other parameters did not differ significantly among centres. Dental inclination variables Ui\u2013PP and Li\u2013MP also showed no significant differences. Inter\u2010rater reliability was moderate to good, with ICC values of 0.51\u20130.85.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Considerable intercentre variation was observed in sagittal hard\u2010 and soft\u2010tissue craniofacial parameters among children with repaired unilateral cleft lip and palate. However, these variations cannot be attributed to any single component of the treatment protocol. Instead, it reflects the multifactorial nature of cleft care, including variations in surgical timing, technique, presurgical orthopaedics and patient\u2010related factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ocr.70152","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:47:21Z","timestamp":1780462041000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Indiacran: An Intercentre Assessment of Craniofacial Form for Patients With Repaired Complete Unilateral Cleft Lip and Palate"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4201-4235","authenticated-orcid":false,"given":"Puneet","family":"Batra","sequence":"first","affiliation":[{"name":"Manav Rachna Dental College, MRIIRS  Faridabad Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9265-8691","authenticated-orcid":false,"given":"Garima","family":"Arora","sequence":"additional","affiliation":[{"name":"Manav Rachna Dental College, MRIIRS  Faridabad Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhinav Raj","family":"Gupta","sequence":"additional","affiliation":[{"name":"G.S. Memorial Plastic Surgery Hospital and Trauma Center  Varanasi UP India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Bhamre","sequence":"additional","affiliation":[{"name":"Amandeep Hospital  Amritsar Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Vivekanand Polyclinic  Lucknow UP India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asif","family":"Masood","sequence":"additional","affiliation":[{"name":"Savitri Hospital and Research Centre  Gorakhpur Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1874-6321","authenticated-orcid":false,"given":"Hemwati","family":"Nandan","sequence":"additional","affiliation":[{"name":"GSR Institute of Cranio\u2010Maxillofacial and Facial Plastic Surgery  Hyderabad Telangana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himanshu","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Vivekanand Polyclinic  Lucknow UP India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isha","family":"Jain","sequence":"additional","affiliation":[{"name":"Savitri Hospital and Research Centre  Gorakhpur Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaideep Singh","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Smile Train, Care CHL  Indore Madhya Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamlesh","family":"Singh","sequence":"additional","affiliation":[{"name":"Vivekanand Polyclinic  Lucknow UP India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7446-7971","authenticated-orcid":false,"given":"Krishnamurthy","family":"Bonanthaya","sequence":"additional","affiliation":[{"name":"Bhagwan Mahaveer Jain Hospital  Bangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Bhola","sequence":"additional","affiliation":[{"name":"Sharad Pawar Dental College and Hospital  Wardha Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallavi","family":"Daigwane","sequence":"additional","affiliation":[{"name":"Sharad Pawar Dental College and Hospital  Wardha Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pritham N.","family":"Shetty","sequence":"additional","affiliation":[{"name":"Smile Train Cleft Leadership Centre Bhagwan Mahaveer Jain Hospital  Bangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi Kumar","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Amandeep Hospital  Amritsar Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samiksha","family":"Chopra","sequence":"additional","affiliation":[{"name":"Amandeep Hospital  Amritsar Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shibani","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Plastic and Maxillofacial Surgery Ashwini Hospital  Cuttack India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruti","family":"Bijapur","sequence":"additional","affiliation":[{"name":"Bhagwan Mahaveer Jain Hospital  Bangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9720-5501","authenticated-orcid":false,"given":"Srinivas Gosla","family":"Reddy","sequence":"additional","affiliation":[{"name":"GSR Institute of Cranio\u2010Maxillofacial and Facial Plastic Surgery  Hyderabad Telangana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subodh Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":"G.S. Memorial Plastic Surgery Hospital and Trauma Center  Varanasi UP India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukhdeep Singh","family":"Kahlon","sequence":"additional","affiliation":[{"name":"Amandeep Hospital  Amritsar Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. C.","family":"Sood","sequence":"additional","affiliation":[{"name":"Sant Parmanand Hospital  Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suryakant","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Orthodontics SCB Dental College and Hospital  Cuttack India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarun","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Amandeep Hospital  Amritsar Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virag","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Smile Train, Care CHL  Indore Madhya Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"issue":"3","key":"e_1_2_13_2_1","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1597\/09-185.1","article-title":"The Americleft Study: An Inter\u2010Center Study of Treatment Outcomes for Patients With Unilateral Cleft Lip and Palate Part 3. 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O.","year":"2015","journal-title":"Cleft Palate\u2010Craniofacial Journal"},{"issue":"1","key":"e_1_2_13_11_1","first-page":"12","article-title":"The Outcomes of Modified Millard Technique Versus Tennison\u2010Randall Technique in Unilateral Cleft Lip Repair: A Comparative Trial","volume":"21","author":"Abdullateef K. S.","year":"2024","journal-title":"African Journal of Paediatric Surgery"},{"issue":"4","key":"e_1_2_13_12_1","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1097\/PRS.0b013e3181d45143","article-title":"Comparison of Three Incisions to Repair Complete Unilateral Cleft Lip","volume":"125","author":"Gosla Reddy S.","year":"2010","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"3","key":"e_1_2_13_13_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.61186\/wjps.12.3.94","article-title":"Comparison of the Outcomes of Surgical Repair of Cleft Palate Performed by Modified Von Langenbeck and Bardach (Two\u2010Flap Palatoplasty) Methods","volume":"12","author":"Peyvasteh M.","year":"2023","journal-title":"World Journal of Plastic Surgery"},{"issue":"4","key":"e_1_2_13_14_1","doi-asserted-by":"crossref","first-page":"188","DOI":"10.3109\/2000656X.2011.583493","article-title":"Factors That Affect Variability in Impairment of Maxillary Growth in Patients With Cleft Lip and Palate Treated Using the Same Surgical Protocol","volume":"45","author":"Meazzini M. 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Part 1: Craniofacial Morphology","volume":"44","author":"Urbanova W.","year":"2016","journal-title":"Journal of Cranio\u2010Maxillo\u2010Facial Surgery"},{"issue":"10","key":"e_1_2_13_19_1","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.ijom.2010.01.024","article-title":"Cleft Size at the Time of Palate Repair in Complete Unilateral Cleft Lip and Palate as an Indicator of Maxillary Growth","volume":"39","author":"Liao Y. F.","year":"2010","journal-title":"International Journal of Oral and Maxillofacial Surgery"},{"issue":"1","key":"e_1_2_13_20_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.4103\/0970-0358.96602","article-title":"A Clinical and Demographic Profile of the Cleft Lip and Palate in Sub\u2010Himalayan India: A Hospital\u2010Based Study","volume":"45","author":"Dvivedi J.","year":"2012","journal-title":"Indian Journal of Plastic Surgery"},{"key":"e_1_2_13_21_1","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.4103\/0970-0358.57182","article-title":"Addressing the Challenges of Cleft Lip and Palate Research in India","volume":"42","author":"Mossey P.","year":"2009","journal-title":"Indian Journal of Plastic Surgery"},{"issue":"3","key":"e_1_2_13_22_1","first-page":"278","article-title":"Demographic Profile of Patients With Cleft Lip and Palate Anomaly: 15\u2010Year Experience From a Tertiary Care Hospital and Teaching Institute in Wardha District of Maharashtra, India","volume":"16","year":"2023","journal-title":"International Journal of Clinical Pediatric Dentistry"},{"issue":"2","key":"e_1_2_13_23_1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ajodo.2010.04.033","article-title":"Initial Cleft Severity and Maxillary Growth in Patients With Complete Unilateral Cleft Lip and Palate","volume":"140","author":"Chiu Y. 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