{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:18:48Z","timestamp":1786115928685,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This exploratory split\u2010mouth randomized controlled trial aimed to evaluate the effect of a custom three\u2010dimensional (3D) surgical guide on mandibular sagittal split osteotomy outcomes compared with conventional freehand osteotomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients undergoing sagittal split osteotomy (SSO) were randomly assigned in a split\u2010mouth design to receive mandibular osteotomy performed with a custom\u2010made 3D surgical guide on one side and without a surgical guide on the contralateral side. The primary outcome was the postoperative lingual split scale (LSS) of the mandible. Secondary outcomes were lateral osteotomy end (LOE), assessed using postoperative CT\u2010based evaluation, and intraoperative inferior alveolar nerve exposure (NE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifteen patients contributed 30 mandibular sides for paired analysis. Guided sides showed more favourable LSS (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.041) and LOE (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.041) distributions compared with non\u2010guided sides. No statistically significant difference was observed in NE (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.763). These findings suggest that the use of a custom 3D surgical guide may improve osteotomy control and split predictability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The custom 3D surgical guide was associated with more favourable lingual split pattern and lateral osteotomy end distributions during sagittal split osteotomy. Given that the study population consisted predominantly of skeletal Class III patients, these findings should be interpreted primarily within the context of Class III patients. No significant reduction in intraoperative inferior alveolar nerve exposure was observed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ocr.70163","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T04:16:06Z","timestamp":1784261766000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of a Custom Three\u2010Dimensional Surgical Guide in Mandibular Sagittal Split Osteotomy: An Exploratory Split\u2010Mouth Randomized Controlled Trial"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1082-8672","authenticated-orcid":false,"given":"Evy Eida","family":"Vitria","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Faculty of Dentistry Universitas Indonesia  DKI Jakarta Jakarta Pusat Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4679-0100","authenticated-orcid":false,"given":"Revini","family":"Nuita","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Faculty of Dentistry Universitas Indonesia  DKI Jakarta Jakarta Pusat Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8605-7651","authenticated-orcid":false,"given":"Muhammad Kamil","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2445-1618","authenticated-orcid":false,"given":"Nissia","family":"Ananda","sequence":"additional","affiliation":[{"name":"Department Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry Universiti Malaya  Kuala Lumpur Malaysia"},{"name":"Dental Unit, Universitas Indonesia Hospital Universitas Indonesia  Depok West Java Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tan Wui","family":"Jing","sequence":"additional","affiliation":[{"name":"Department Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3829-023X","authenticated-orcid":false,"given":"Zakiah","family":"Mat Ripen","sequence":"additional","affiliation":[{"name":"Department Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2481-2893","authenticated-orcid":false,"given":"Norliza","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry Universiti Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpsurg.2024.101587"},{"key":"e_1_2_11_3_1","volume-title":"Historical Evolution of Orthognathic Surgery","author":"Naini F. 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