{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:10:35Z","timestamp":1789013435074,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Orthod Craniofacial Res"],"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that may influence oral health and orthodontic characteristics due to associated behavioural, sensory, and motor challenges. This study aimed to compare orthodontic treatment need, Angle classification, and oral hygiene status between children with ASD and typically developing children.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n This cross\u2010sectional comparative study included 50 children aged 6\u201318\u2009years with ASD and 43 age\u2010 and sex\u2010matched typically developing children. Malocclusion and orthodontic treatment need were assessed using Angle classification and the Index of Complexity, Outcome, and Need (ICON), respectively. Oral hygiene was evaluated with the Simplified Oral Hygiene Index (OHI\u2010S). Intra\u2010rater reliability was assessed with the intraclass correlation coefficient (ICC\u2009=\u20090.96). Group differences were assessed using the Mann\u2013Whitney\n U<\/jats:italic>\n , chi\u2010square, or Fisher's exact tests, as appropriate. Spearman's correlation and age\u2010 and sex\u2010adjusted multivariable regression analyses were also performed.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n ICON<\/jats:styled-content>\n scores were significantly higher in children with\n ASD<\/jats:styled-content>\n than in typically developing children (\n p<\/jats:italic>\n \u2009=\u20090.024). Oral hygiene was significantly poorer in the\n ASD<\/jats:styled-content>\n group (\n p<\/jats:italic>\n \u2009<\u20090.001), whereas Angle classification did not differ significantly between the groups (\n p<\/jats:italic>\n \u2009=\u20090.118). After adjustment for age and sex,\n ASD<\/jats:styled-content>\n diagnosis remained significantly associated with higher\n ICON<\/jats:styled-content>\n scores (adjusted B\u2009=\u20099.74, 95%\n CI<\/jats:styled-content>\n : 2.95\u201316.53,\n p<\/jats:italic>\n \u2009=\u20090.005) and greater odds of being classified in a poorer oral hygiene category (adjusted\n OR<\/jats:styled-content>\n \u2009=\u20094.65, 95%\n CI<\/jats:styled-content>\n : 2.05\u201310.56,\n p<\/jats:italic>\n \u2009<\u20090.001).\n CARS<\/jats:styled-content>\n scores were not significantly correlated with\n ICON<\/jats:styled-content>\n scores (rho\u2009=\u2009\u22120.152,\n p<\/jats:italic>\n \u2009=\u20090.291).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Within the limitations of this study sample, children with ASD showed higher ICON scores and poorer oral hygiene status compared with typically developing children. These findings indicate an association between ASD status, orthodontic treatment need as assessed by ICON, and oral hygiene status in the study population. Further studies are needed to better understand the factors influencing orthodontic and oral health outcomes in children with ASD.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ocr.70181","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:56:15Z","timestamp":1789012575000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Orthodontic and Oral Health Assessment in Children With Autism: A Comparative Study With Typically Developing Children"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9466-8447","authenticated-orcid":false,"given":"Mevl\u00fcde Y\u00fcce","family":"Polat","sequence":"first","affiliation":[{"name":"Department of Orthodontics, Head of the Department of Orthodontics, Faculty of Dentistry Harran University \u015eanl\u0131urfa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8131-8859","authenticated-orcid":false,"given":"Fethiye","family":"K\u0131l\u0131\u00e7aslan","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Faculty of Medicine Harran University \u015eanl\u0131urfa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,9]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders (DSM\u2010V)","author":"American Psychiatric Association (APA)","year":"2013"},{"issue":"5","key":"e_1_2_13_3_1","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1002\/aur.2696","article-title":"Global Prevalence of Autism: A Systematic Review Update","volume":"15","author":"Zeidan J. 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