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All regular medications were recorded and classified according to the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>natomical <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>herapeutic <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hemical <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lassification <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ystem.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> used thyroid preparations (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and non\u2010steroidal anti\u2010inflammatory drugs (<jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>s) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01) in higher proportions compared to controls. A multivariate logistic regression model demonstrated that levothyroxine was associated with <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> (multivariate <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 3.39, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 2.09\u20135.46, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), even after controlling for confounders, including age, sex, smoking, allergies and systemic diseases. No statistical significance could be found between <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>s and <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> using the same model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this study, the use of levothyroxine was associated with <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>, which in turn suggests a possible connection with hypothyroidism.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12009","type":"journal-article","created":{"date-parts":[[2012,8,6]],"date-time":"2012-08-06T02:33:22Z","timestamp":1344220402000},"page":"313-319","source":"Crossref","is-referenced-by-count":20,"title":["Use of systemic medication in patients with oral lichen planus \u2013 a possible association with hypothyroidism"],"prefix":"10.1111","volume":"19","author":[{"given":"J","family":"Robledo\u2010Sierra","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Pathology Institute of Odontology Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U","family":"Mattsson","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Pathology Institute of Odontology Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Jontell","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Pathology Institute of Odontology Sahlgrenska Academy University of Gothenburg Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.2.561"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"S25e1","DOI":"10.1016\/j.tripleo.2006.11.001","article-title":"Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations","volume":"103","author":"Al\u2010Hashimi I","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2007.00581.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2004.01024.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1430639"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.195032"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2009.01516.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1996.tb01726.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2008.00686.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2009.03581.x"},{"key":"e_1_2_6_12_1","first-page":"69","article-title":"Ativan (lorazepam) induced lichenoid reaction of the human attached gingiva: case report","volume":"8","author":"Colvard MD","year":"1986","journal-title":"Periodontal Case Rep"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2010.09.074"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5584.100"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09235.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-009-9258-z"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.03.004"},{"key":"e_1_2_6_18_1","first-page":"39","article-title":"Oral mucosal lichenoid eruption due to fenclofenac","volume":"39","author":"Ferguson MM","year":"1984","journal-title":"J Oral Med"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(93)90013-T"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6401.1258"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4804144"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.17095"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.01.009"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.2003.02892.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2008.00702.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2010.00897.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(78)90383-3"},{"key":"e_1_2_6_28_1","unstructured":"L\u00e4kemedelsindustrif\u00f6reningen(2012).FASS ATC\u2010register. 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