{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:32:06Z","timestamp":1787063526064,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,10,3]],"date-time":"2012-10-03T00:00:00Z","timestamp":1349222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      The aim of this study is to characterize immunohistochemical profiles of lining epithelia of nasopalatine duct cyst (\n                      <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                      ) as well as to correlate those findings with their clinicopathological features to understand the histopathogenesis of\n                      <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      Forty\u2010one surgical specimens from\n                      <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                      were examined for clinical profiles and expression of keratin\u20107, 13,\n                      <jats:styled-content style=\"fixed-case\">MUC<\/jats:styled-content>\n                      \u20101, and\n                      <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\n                      63 by immunohistochemistry, compared to radicular cyst (\n                      <jats:styled-content style=\"fixed-case\">RC<\/jats:styled-content>\n                      ) and maxillary sinusitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nasopalatine duct cyst was clinically characterized by male predominant occurrence: 44% of the cases involved tooth roots, and 70% with inflammatory backgrounds. Lining epithelia of\n                      <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                      s without daughter cysts were immunohistochemically distinguished into three layers: a keratin 7\u2010positive (+) ciliated cell layer in the surface, a keratin\u201013+ middle layer, and a\n                      <jats:styled-content style=\"fixed-case\">MUC<\/jats:styled-content>\n                      \u20101+\/P63+ lower half, indicating that they were not respiratory epithelia, and the same layering pattern was observed in\n                      <jats:styled-content style=\"fixed-case\">RC<\/jats:styled-content>\n                      . However, those immunolocalization patterns of the main cyst lining with daughter cyst were exactly the same as those of daughter cyst linings as well as duct epithelia of mucous glands.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Two possible histopathogeneses of\n                      <jats:styled-content style=\"fixed-case\">NPC<\/jats:styled-content>\n                      were clarified: one was inflammatory cyst like\n                      <jats:styled-content style=\"fixed-case\">RC<\/jats:styled-content>\n                      and the other was salivary duct cyst\u2010like mucocele.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.12022","type":"journal-article","created":{"date-parts":[[2012,9,13]],"date-time":"2012-09-13T09:59:10Z","timestamp":1347530350000},"page":"415-424","source":"Crossref","is-referenced-by-count":19,"title":["Inflammatory histopathogenesis of nasopalatine duct cyst: a clinicopathological study of 41 cases"],"prefix":"10.1111","volume":"19","author":[{"given":"M","family":"Tsuneki","sequence":"first","affiliation":[{"name":"Division of Oral Pathology Department of Tissue Regeneration and Reconstruction Niigata University Graduate School of Medical and Dental Sciences Niigata Japan"},{"name":"Fellow the Japan Society for the Promotion of Science Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Maruyama","sequence":"additional","affiliation":[{"name":"Oral Pathology Section Department of Surgical Pathology Niigata University Hospital Niigata 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