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Glycerine (control), <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content> were topically applied in group I, II, and III, respectively, and the prognosis of <jats:styled-content style=\"fixed-case\">OM<\/jats:styled-content> was assessed by functional, objective, and subjective parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients of group II and III showed significant improvement when <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>h<jats:styled-content style=\"fixed-case\">ROM<\/jats:styled-content> was analyzed through scoring systems \u2013 <jats:styled-content style=\"fixed-case\">WHO<\/jats:styled-content> grading, Oral Mucositis Assessment Scale (<jats:styled-content style=\"fixed-case\">OMAS<\/jats:styled-content>), and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hildren's <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nternational <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ucositis <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>valuation <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale (<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>h<jats:styled-content style=\"fixed-case\">IMES<\/jats:styled-content>) as compared to group I (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); however, there was no significant difference between groups <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both the drugs <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content> per se are effective for treatment of <jats:styled-content style=\"fixed-case\">OM<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content> being not effective for the treatment of severe mucositis (grade 4). Combination of <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content> and additional agents may be tried for better results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12024","type":"journal-article","created":{"date-parts":[[2012,9,13]],"date-time":"2012-09-13T10:03:13Z","timestamp":1347530593000},"page":"456-464","source":"Crossref","is-referenced-by-count":31,"title":["An evaluation of vitamin <scp>E<\/scp> and pycnogenol in children suffering from oral mucositis during cancer chemotherapy"],"prefix":"10.1111","volume":"19","author":[{"given":"H","family":"Khurana","sequence":"first","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry Faculty of Dental Sciences Chhatrapati Shahuji Maharaj Medical University Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RK","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry Faculty of Dental Sciences Chhatrapati Shahuji Maharaj Medical University Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AK","family":"Saksena","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Chhatrapati Shahuji Maharaj Medical University Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Chhatrapati Shahuji Maharaj Medical University Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-07-035022"},{"key":"e_1_2_8_3_1","first-page":"227","article-title":"Pycnogenol may alleviate adverse effects in oncologic treatment","volume":"50","author":"Belcaro G","year":"2008","journal-title":"Panminerva Med"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(98)00169-5"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.13.10.1145"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2003.10.023"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2001.tb05644.x"},{"key":"e_1_2_8_8_1","first-page":"CD000978","article-title":"Interventions for preventing oral mucositis for patients with cancer receiving treatment","volume":"3","author":"Clarkson JE","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_9_1","first-page":"CD000978","article-title":"Interventions for treating oral mucositis for patients with cancer receiving treatment","volume":"8","author":"Worthington HV","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_10_1","unstructured":"Clinical Trials (PDQ\u00ae) National Cancer Institute at the National Institutes of Health(2011).Supersaturated calcium phosphate rinse in preventing oral mucositis in young patients undergoing autologous or donor stem cell transplant. 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