{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:52:24Z","timestamp":1740124344325,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T00:00:00Z","timestamp":1411344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To analyze the role of smoking, drinking, and their synergistic effect in the occurrence of potentially malignant oral disorders (<jats:styled-content style=\"fixed-case\">PMOD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and methods<\/jats:title><jats:p>We examined three groups: 50 patients with lung cancer, 50 patients with liver cirrhosis, and 50 patients with clear medical history. Scores were developed for drinking, smoking, drinking &amp; smoking, and <jats:styled-content style=\"fixed-case\">PMOD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All four scores were the lowest in the control group. The lung cancer group showed the highest Smoking, Alcohol &amp; Smoking and Lesions score, while the liver cirrhosis group had the Alcohol score the highest. Compared with the control group, lung cancer group is more likely to develop a <jats:styled-content style=\"fixed-case\">PMOD<\/jats:styled-content> than the liver cirrhosis group (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a012.31\/OR\u00a0=\u00a06.71). Statistical significance between the groups was found in the Lesions score (\u03c7<jats:sup>2<\/jats:sup>\u00a0=\u00a015.34; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The patients with lung cancer and liver cirrhosis represent a high\u2010risk group for <jats:styled-content style=\"fixed-case\">PMOD<\/jats:styled-content>. Patients with lung cancer and liver cirrhosis have never, to our knowledge, been categorized as high\u2010risk patients for <jats:styled-content style=\"fixed-case\">PMOD<\/jats:styled-content>. After diagnosed, patients with lung cancer and liver cirrhosis should have a routine oral cavity examination, as they present a high\u2010risk group for <jats:styled-content style=\"fixed-case\">PMOD<\/jats:styled-content> and oral cancer.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12289","type":"journal-article","created":{"date-parts":[[2014,9,2]],"date-time":"2014-09-02T08:23:16Z","timestamp":1409646196000},"page":"373-377","source":"Crossref","is-referenced-by-count":1,"title":["Potentially malignant oral disorders and high\u2010risk habits in liver cirrhosis and lung cancer patients"],"prefix":"10.1111","volume":"21","author":[{"given":"I","family":"Salari\u0107","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Hospital Dubrava School of Dental Medicine University of Zagreb Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Povrzanovi\u0107","sequence":"additional","affiliation":[{"name":"Private Practice Pula Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Brajdi\u0107","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Hospital Dubrava School of Dental Medicine University of Zagreb Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Luk\u0161i\u0107","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Hospital Dubrava School of Medicine University of Zagreb Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8632-8186","authenticated-orcid":false,"given":"D","family":"Macan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Hospital Dubrava School of Dental Medicine University of Zagreb Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds337"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2010.06.010"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12095"},{"key":"e_1_2_7_5_1","first-page":"773","article-title":"The frequency and malignant transformation rate of oral lichen planus and leukoplakia \u2013 a retrospective study","volume":"36","author":"Brzak BL","year":"2012","journal-title":"Coll Antropol"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0602"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12160-013-9480-z"},{"volume-title":"The role of alcohol in the etiology of oral cancer","year":"1999","author":"Macan D","key":"e_1_2_7_8_1"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1744-7895(07)70272-9"},{"key":"e_1_2_7_10_1","first-page":"544","article-title":"Malignant transformation of oral lichen planus. 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