{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:50:19Z","timestamp":1781106619239,"version":"3.54.1"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T00:00:00Z","timestamp":1421884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the clinical characteristics of lichen planus with dysplasia (<jats:styled-content style=\"fixed-case\">LD<\/jats:styled-content>) cases with oral dysplasia (<jats:styled-content style=\"fixed-case\">DYS<\/jats:styled-content>), and <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\/lichenoid reaction (<jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients treated at the Department of Oral Medicine with a histological diagnosis were included. Patient information (age, gender, ethnicity, smoking habits, and medical status) and parameters of oral manifestation (lesions' distribution, site, and type) were compared<jats:bold>.<\/jats:bold><\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Two hundred and thirty five patients were included. 54% were never smokers and 25% were current smokers. The <jats:styled-content style=\"fixed-case\">LD<\/jats:styled-content> group (<jats:italic>n<\/jats:italic>\u00a0=\u00a079) had more bilateral cases when compared to the <jats:styled-content style=\"fixed-case\">DYS<\/jats:styled-content> group (<jats:italic>n<\/jats:italic>\u00a0=\u00a030), 70% to 40.7%, respectively (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.008), and a lower average age [56\u201362, respectively (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.043)]. All other parameters were similar. When compared to <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content> patients, the <jats:styled-content style=\"fixed-case\">LD<\/jats:styled-content> group had a higher percentage of men [41.8\u201327.9%, respectively (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.08)] while all other parameters were similar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As clinical characteristics of <jats:styled-content style=\"fixed-case\">LD<\/jats:styled-content> are more similar to the <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content> group than to dysplasia, these findings may indicate that <jats:styled-content style=\"fixed-case\">LD<\/jats:styled-content> should be considered as part of the lichen planus disorder spectrum rather than a separate entity, although further analysis of larger groups is warranted. These results support the need for clinical follow\u2010up among patients diagnosed with lichenoid changes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12306","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T04:15:08Z","timestamp":1418098508000},"page":"478-482","source":"Crossref","is-referenced-by-count":13,"title":["Clinical characteristics of lichen and dysplasia <i>vs<\/i> lichen planus cases and dysplasia cases"],"prefix":"10.1111","volume":"21","author":[{"given":"R","family":"Czerninski","sequence":"first","affiliation":[{"name":"Department of Oral Medicine Hebrew University\u2010Hadassah School of Dental Medicine Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Zeituni","sequence":"additional","affiliation":[{"name":"Hebrew University\u2010Hadassah School of Dental Medicine Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Maly","sequence":"additional","affiliation":[{"name":"Department of Pathology Hadassah Medical Center Jerusalem Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Basile","sequence":"additional","affiliation":[{"name":"Department of Oncology and Diagnostic Sciences University of Maryland Dental School Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,22]]},"reference":[{"issue":"25","key":"e_1_2_6_2_1","first-page":"e1","article-title":"Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations","volume":"103","author":"Al\u2010Hashimi I","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2009.00782.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/joms.2000.16629"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2013.12.413"},{"key":"e_1_2_6_6_1","first-page":"177","volume-title":"Pathology and genetics of tumors of the head and neck","author":"Gale N","year":"2005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2014.01.007"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2012.04.002"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.49.89"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1103641"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.06.076"},{"key":"e_1_2_6_12_1","unstructured":"Ministry of Health(2012).Annual report \u2013smoking in Israel published May 2013http:\/\/www.health.gov.il\/PublicationsFiles\/smoking-2012.pdf[accessed on 15 December 2014]"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(03)00305-6"},{"key":"e_1_2_6_14_1","first-page":"E310","article-title":"Oral lichen planus and oral lichenoid lesions' a critical appraisal with emphasis on the diagnostic aspects","volume":"14","author":"Waal I","year":"2009","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2010.02.016"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20205"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fodi.12306","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.12306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T21:44:36Z","timestamp":1696283076000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.12306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,22]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/odi.12306"],"URL":"https:\/\/doi.org\/10.1111\/odi.12306","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,22]]}}}