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The occurrence of <jats:styled-content style=\"fixed-case\">ONJ<\/jats:styled-content> is higher in oncology patients treated with high\u2010dose iv bisphosphonates than in osteoporosis patients treated with oral bisphosphonates. Although multiple hypotheses have been proposed, the exact pathogenic mechanism of <jats:styled-content style=\"fixed-case\">ONJ<\/jats:styled-content> still remains unclear. As treatment protocols based on randomized controlled trials (<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s) do not exist, we critically reviewed the existing data concerning the management of bisphosphonate\u2010related osteonecrosis of the jaw, including the most recent data for the use of teriparatide and hyperbaric oxygen.<\/jats:p>","DOI":"10.1111\/odi.12333","type":"journal-article","created":{"date-parts":[[2015,3,2]],"date-time":"2015-03-02T19:24:22Z","timestamp":1425324262000},"page":"927-936","source":"Crossref","is-referenced-by-count":33,"title":["Management of bisphosphonate\u2010related osteonecrosis of the jaw: a literature review"],"prefix":"10.1111","volume":"21","author":[{"given":"A","family":"Spanou","sequence":"first","affiliation":[{"name":"Postgraduate Course on Metabolic Bone Disease Faculty of Medicine University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GP","family":"Lyritis","sequence":"additional","affiliation":[{"name":"Postgraduate Course on Metabolic Bone Disease Faculty of Medicine University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Chronopoulos","sequence":"additional","affiliation":[{"name":"Postgraduate Course on Metabolic Bone Disease Faculty of Medicine University of Athens Athens Greece"},{"name":"2nd Orthopaedic Department Konstantopoulion Hospital University of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Tournis","sequence":"additional","affiliation":[{"name":"Laboratory for Research of the Musculoskeletal System \u2018Th. 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