{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T23:42:14Z","timestamp":1779147734130,"version":"3.51.4"},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,12,4]],"date-time":"2015-12-04T00:00:00Z","timestamp":1449187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81000441"],"award-info":[{"award-number":["81000441"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:p>The objective of this study is to assess the efficacy and safety of miconazole for treating oral candidiasis. Twelve electronic databases were searched for randomized controlled trials evaluating treatments for oral candidiasis and complemented by hand searching. The clinical and mycological outcomes, as well as adverse effects, were set as the primary outcome criteria. Seventeen trials were included in this review. Most studies were considered to have a high or moderate level of bias. Miconazole was more effective than nystatin for thrush. For <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients, there was no significant difference in the efficacy between miconazole and other antifungals. For denture wearers, microwave therapy was significantly better than miconazole. No significant difference was found in the safety evaluation between miconazole and other treatments. The relapse rate of miconazole oral gel may be lower than that of other formulations. This systematic review and meta\u2010analysis indicated that miconazole may be an optional choice for thrush. Microwave therapy could be an effective adjunct treatment for denture stomatitis. Miconazole oral gel may be more effective than other formulations with regard to long\u2010term results. However, future studies that are adequately powered, large\u2010scale, and well\u2010designed are needed to provide higher\u2010quality evidence for the management of oral candidiasis.<\/jats:p>","DOI":"10.1111\/odi.12380","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T00:25:19Z","timestamp":1444695919000},"page":"185-195","source":"Crossref","is-referenced-by-count":63,"title":["Efficacy and safety of miconazole for oral candidiasis: a systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"22","author":[{"given":"L\u2010W","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Oral Medicine Peking University School and Hospital of Stomatology Haidian District Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u2010Y","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of stomatology Peking University International Hospital Changping District Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Hua","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Peking University School and Hospital of Stomatology Haidian District Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z\u2010M","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Peking University School and Hospital of Stomatology Haidian District Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.1986"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2009.0874"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2003.12.028"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05947-11"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23152"},{"key":"e_1_2_8_7_1","first-page":"20","article-title":"Epidemiology of oropharyngeal candidiasis in human immunodeficiency virus\/acquired immune deficiency syndrome patients and CD4+ counts","volume":"7","author":"Berberi A","year":"2015","journal-title":"J Int Oral Health"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.1994.tb00789.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/947980"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2004.02154.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51242"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2013.11.021"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-849X.2011.00698.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199703000-00007"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01713319"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2008.00986.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0507.2009.01728.x"},{"key":"e_1_2_8_18_1","first-page":"1","article-title":"Guidelines for prevention and treatment of opportunistic infections in HIV\u2010infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America","volume":"58","author":"Kaplan JE","year":"2009","journal-title":"MMWR Recomm Rep"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(94)90059-0"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.152"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ebd.6401032"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-010-0892-z"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.4161\/viru.20746"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12337"},{"key":"e_1_2_8_25_1","first-page":"379","article-title":"Is denture stomatitis always related with candida infection? 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