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How <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> infection disrupts <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4 T\u2010cell function, which specifically compromises host immunity to <jats:italic>Mycobacterium tuberculosis,<\/jats:italic> is poorly understood and is a critical roadblock in developing better vaccine\u2010 or immune\u2010based strategies to control and monitor <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected subjects. 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