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Also quality of life needs further investigation supported by better study designs and improvement of the instruments used. Up\u2010to\u2010date evidence suggested long\u2010term harms associated with <jats:italic>in utero<\/jats:italic> antiretroviral exposure were minor but would require long\u2010term follow\u2010up through National Registries. The reviews also revealed the wide spectrum of metabolic disease due to antiretroviral therapy and co\u2010infections such as tuberculosis. Finally, atraumatic restorative technique appears to be a simple and safe technique to treat dental caries but outcomes need further evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The impact of antiretroviral therapy in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected children has raised novel challenging questions in the field of oral health warranting future research.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12417","type":"journal-article","created":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T13:44:45Z","timestamp":1455630285000},"page":"149-157","source":"Crossref","is-referenced-by-count":7,"title":["The global burden of oral diseases in pediatric <scp>HIV<\/scp>\u2010infected populations: a workshop report"],"prefix":"10.1111","volume":"22","author":[{"given":"E","family":"Arrive","sequence":"first","affiliation":[{"name":"UFR d'Odontologie University of Bordeaux Bordeaux France"},{"name":"Equipe VIH et Sant\u00e9 Globale INSERM U897 Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Meless","sequence":"additional","affiliation":[{"name":"UFR d'Odontostomatologie F\u00e9lix Houphou\u00ebt Boigny University of Abidjan Abidjan C\u00f4te d'Ivoire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Anaya\u2010Saavedra","sequence":"additional","affiliation":[{"name":"Department of Health Care Universidad Aut\u00f3noma Metropolitana\u2010Xochimilco M\u00e9xico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Gallottini","sequence":"additional","affiliation":[{"name":"Department of Stomatology School of Dentistry University of Sao Paulo Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LM","family":"Pinzon","sequence":"additional","affiliation":[{"name":"School of Dentistry University of California San Francisco CA USA"},{"name":"School of Dentistry University of Utah Salt Lake City UT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Ramirez\u2010Amador","sequence":"additional","affiliation":[{"name":"Department of Health Care Universidad Aut\u00f3noma Metropolitana\u2010Xochimilco M\u00e9xico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0300-1652.104385"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200205000-00011"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1086\/498511"},{"key":"e_1_2_6_5_1","unstructured":"Antiretroviral Pregnancy Registry Steering Committee(2014).Antiretroviral Pregnancy Registry International Interim Report for 1 January 1989 through January 2014.Registry Coordinating Center:Wilmington NC. 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