{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T05:13:02Z","timestamp":1779167582105,"version":"3.51.4"},"reference-count":48,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T00:00:00Z","timestamp":1461628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To relate five periodontopathogenic bacteria, including the red complex, to the severity, extent, and inflammation of the periodontal lesion in Caucasian patients with generalized aggressive and chronic periodontitis and to explore whether tobacco use is associated with a specific bacterial profile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A cross\u2010sectional and analytic study was conducted in patients with aggressive and chronic periodontitis. Data were gathered on socio\u2010demographic and periodontal variables, and <jats:styled-content style=\"fixed-case\">RH<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> was used to determine subgingival bacterial profile. Linear and logistic regression analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included 60 patients with aggressive and 123 with chronic periodontitis. Total red complex bacteria count was higher in aggressive periodontitis, mainly due to <jats:italic>T.\u00a0denticola<\/jats:italic> (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.015). In both periodontitis types, models showed an association between <jats:italic>T.\u00a0forsythia<\/jats:italic> count and probing depth (B\u00a0=\u00a00.157, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.030) and between <jats:italic>T.\u00a0denticola<\/jats:italic> count and higher bleeding scores (B\u00a0=\u00a02.371, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.027). Smoking did not affect the red complex bacteria count in either disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prevalence of red complex bacteria was similar between aggressive and chronic periodontitis, but their count was higher in the former. In both diseases, <jats:italic>T.\u00a0forsythia<\/jats:italic> was associated with greater severity and <jats:italic>T.\u00a0denticola<\/jats:italic> with more severe bleeding. Tobacco smoking was not associated with the presence of red complex bacteria in either disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12471","type":"journal-article","created":{"date-parts":[[2016,3,7]],"date-time":"2016-03-07T09:50:47Z","timestamp":1457344247000},"page":"430-437","source":"Crossref","is-referenced-by-count":24,"title":["Complementary clinical effects of red complex bacteria on generalized periodontitis in a caucasian population"],"prefix":"10.1111","volume":"22","author":[{"given":"E","family":"Lanza","sequence":"first","affiliation":[{"name":"Private Periodontology Practice Malaga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6430-2276","authenticated-orcid":false,"given":"A","family":"Magan\u2010Fernandez","sequence":"additional","affiliation":[{"name":"Periodontology Department School of Dentistry University of Granada Granada 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