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This chronic disease has a significant impact on the orofacial region that is involved in more than two\u2010thirds of the cases. <jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content>c patients can show a wide array of oral manifestations, which are usually associated with a severe impairment of the quality of life. They often present a decreased the salivary flow and a reduced mouth opening that contribute substantially to the worsening of the oral health status. Therefore, <jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content>c patients require specific and multidisciplinary interventions that should be initiated as early as possible. The identification of specific radiological and clinical signs at the early stage will improve the management of such patients. 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