{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T09:29:08Z","timestamp":1776331748995,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate changes in the levels of gingival crevicular fluid (<jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content>) chemerin and interleukin\u20106 (<jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106) in both obese\/non\u2010obese individuals with\u00a0periodontitis following non\u2010surgical periodontal therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Individuals (<jats:italic>n<\/jats:italic>\u00a0=\u00a080) were split into four groupings according to periodontal\/anthropometric parameters: (i) periodontal healthy without obesity; (ii) chronic periodontitis (<jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content>) without obesity; (iii) periodontal healthy with obesity; and (iv) <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> with obesity. Individuals with periodontitis were treated with non\u2010surgical periodontal therapy. Both <jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content> sampling procedures and clinical periodontal measures were performed prior to treatment and 6\u00a0weeks thereafter. Enzyme\u2010linked immunosorbent assay was utilized to measure both chemerin and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106 levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Greater values for chemerin and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106 were observed in obese individuals compared to their non\u2010obese controls and in individuals with <jats:styled-content style=\"fixed-case\">CP<\/jats:styled-content> compared to their periodontal healthy controls (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.008), which decreased following therapy (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). A positive correlation was found between chemerin and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106 in obese groups (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). A comprehensive overview of all groups showed a statistically significant positive correlation among chemerin, along with <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20106, waist\u2010to\u2010hip ratio, body mass index, and clinical attachment levels (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>It could be concluded that chemerin levels may act as both diagnostic and prognostic indicators. Chemerin may also play an integral part in the pathologic mechanisms that relate adipokines to both periodontal disease and obesity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12520","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T06:33:17Z","timestamp":1465194797000},"page":"673-680","source":"Crossref","is-referenced-by-count":23,"title":["Chemerin and interleukin\u20106 levels in obese individuals following periodontal treatment"],"prefix":"10.1111","volume":"22","author":[{"given":"U","family":"Balli","sequence":"first","affiliation":[{"name":"Department of Periodontology Faculty of Dentistry Bulent Ecevit University Zonguldak Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Ongoz Dede","sequence":"additional","affiliation":[{"name":"Department of Periodontology Faculty of Dentistry Ordu University Ordu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Bozkurt 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