{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:56:40Z","timestamp":1787500600126,"version":"build-2736575974"},"reference-count":100,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,9]],"date-time":"2017-03-09T00:00:00Z","timestamp":1489017600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2016R1A2B4007286"],"award-info":[{"award-number":["2016R1A2B4007286"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2016R1A2B4007286"],"award-info":[{"award-number":["2016R1A2B4007286"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002551","name":"Seoul National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002551","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To propose the application of the concept of geriatric syndrome for common geriatric oral and maxillofacial dysfunctions and to suggest the necessity of developing effective evaluation methods for oral and maxillofacial frailty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>The concepts of frailty and geriatric syndrome based on multi\u2010morbidity and polypharmacy were applied to five common geriatric oral medicinal dysfunctional problems: salivary gland hypofunction (dry mouth), chronic oral mucosal pain disorders (burning mouth symptoms), taste disorders (taste disturbances), swallowing disorders (dysphagia), and oral and maxillofacial movement disorders (oromandibular dyskinesia and dystonia).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Each of the dysfunctions is caused by various kinds of diseases and\/or conditions and medications, thus the concept of geriatric syndrome could be applied. These dysfunctions, suggested as components of oral and maxillofacial geriatric syndrome, are associated and interacted with each other in a complexity of vicious cycle. The resulting functional impairments caused by this syndrome can cause oral and maxillofacial frailty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Geriatric oral and maxillofacial dysfunctions could be better appreciated in the context of geriatric syndrome. The development of effective methods for evaluating the severity of these dysfunctions and the resulting frailty is essential.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.12647","type":"journal-article","created":{"date-parts":[[2017,1,31]],"date-time":"2017-01-31T19:12:45Z","timestamp":1485889965000},"page":"317-324","source":"Crossref","is-referenced-by-count":27,"title":["Geriatric oral and maxillofacial dysfunctions in the context of geriatric syndrome"],"prefix":"10.1111","volume":"24","author":[{"given":"Y","family":"Nam","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Oral Diagnosis School of Dentistry and Dental Research Institute Seoul National University Jongno\u2010gu Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u2010H","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dental Hygiene Wonju College of Medicine Yonsei University Wonju Gangwon\u2010do Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9960-9892","authenticated-orcid":false,"given":"H\u2010S","family":"Kho","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Oral Diagnosis School of Dentistry and Dental Research Institute Seoul National University Jongno\u2010gu Seoul Korea"},{"name":"Institute on Aging Seoul National University Gwanak\u2010Gu Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.78.922.455"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.0022-0337.1990.54.11.tb02481.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2007.12.010"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjh192"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(86)90095-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0885-4505(86)90134-9"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1999.tb02052.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12094"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20130"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1H036"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(97)90316-4"},{"key":"e_1_2_9_13_1","first-page":"143","article-title":"Dysphagia associated with neurological disorders","volume":"48","author":"Buchholz D","year":"1993","journal-title":"Acta Otorhinolaryngol Belg"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afp100"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2008.10.004"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2001.0088"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(97)03031-X"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7375.1277"},{"key":"e_1_2_9_19_1","first-page":"870","article-title":"The development and validation of a dysphagia\u2010specific quality\u2010of\u2010life questionnaire for patients with head and neck cancer \u2013 the M. D. Anderson dysphagia inventory","volume":"127","author":"Chen AY","year":"2001","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"e_1_2_9_20_1","first-page":"97","article-title":"Candesartan induced ageusia and stomatitis: case report","volume":"25","author":"Chen C","year":"2004","journal-title":"Nephrologie"},{"key":"e_1_2_9_21_1","first-page":"433","article-title":"Frailty syndrome: an overview","volume":"9","author":"Chen X","year":"2014","journal-title":"Clin Interv Aging"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61460-4"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1088665"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1Z434"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1977.tb01431.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.157.1.131"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.07.030"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(02)00052-0"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.M146"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/59.3.M255"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.1.109"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjopharm.2007.12.002"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0920-9964(95)00096-8"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2007.01156.x"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2011.11.006"},{"key":"e_1_2_9_36_1","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0011-8532(22)00043-X","article-title":"Periodontal care","volume":"41","author":"Kamen PR","year":"1997","journal-title":"Dent Clin North Am"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.01.030"},{"key":"e_1_2_9_38_1","first-page":"254","article-title":"Integrating incidence and prevalence of tardive dyskinesia","volume":"22","author":"Kane JM","year":"1986","journal-title":"Psychopharmacol Bull"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.50.5935"},{"key":"e_1_2_9_40_1","first-page":"75","article-title":"Understanding of xerostomia and strategies for the development of artificial saliva","volume":"17","author":"Kho HS","year":"2014","journal-title":"Chin J Dent Res"},{"key":"e_1_2_9_41_1","first-page":"185","article-title":"Epidemiology and pathophysiology of tardive dyskinesias","volume":"49","author":"Klawans HL","year":"1988","journal-title":"Adv Neurol"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13613"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12345"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.278.5337.419"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-198506000-00005"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02414429"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(98)90273-8"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.570564"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v64n0317b"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00009583"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.15.e562"},{"key":"e_1_2_9_52_1","first-page":"56","article-title":"Taste changes and saliva composition in chronic kidney disease","volume":"8","author":"Manley KJ","year":"2012","journal-title":"Renal Soc Australas J"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1159\/000016094"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.68.2.196"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2007.121137"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2011.03.003"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00262751"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-008-9185-9"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(75)90394-0"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004550010013"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-001-0109-1"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2014.09.011"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-015-0565-x"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e3283589f63"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00714599"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(96)80410-0"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-010-0419-5"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02274896"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870030302"},{"key":"e_1_2_9_70_1","first-page":"83","article-title":"Geriatric syndromes: medical misnomer or progress in geriatrics?","volume":"61","author":"Olde Rikkert MG","year":"2003","journal-title":"Neth J Med"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.05.009"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1982.04290040052008"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2001.111551"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1258\/1362180053654510"},{"key":"e_1_2_9_75_1","first-page":"271","article-title":"Electrogustometry thresholds, tongue tip vascularization, and density and morphology of the fungiform papillae in diabetes","volume":"10","author":"Pavlidis P","year":"2014","journal-title":"B\u2010ENT"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.4140\/TCP.n.2016.267"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2003.07.010"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1177\/106002809202601109"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1177\/154411130301400405"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870050411"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1993.0137"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/50A.5.M285"},{"key":"e_1_2_9_83_1","first-page":"175","article-title":"Tardive dyskinesia rating scales","volume":"14","author":"Simpson GM","year":"1988","journal-title":"Encephale"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1997.tb00941.x"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00009533"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1111\/ger.12001"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.1997.00033.x"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25244"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5300-6"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1177\/106002809002400320"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2006.01325.x"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S37477"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480260046391"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2004.01002.x"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.2165\/11593120-000000000-00000"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2007.0358"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/63.2.190"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.284.6330.1672"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.20.2333"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/48.5.M219"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2015.1032244"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fodi.12647","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.12647","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T19:39:10Z","timestamp":1695670750000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.12647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,9]]},"references-count":100,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1111\/odi.12647"],"URL":"https:\/\/doi.org\/10.1111\/odi.12647","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,9]]}}}