{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T08:29:41Z","timestamp":1768984181418,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T00:00:00Z","timestamp":1505779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2018,4]]},"abstract":"Objective<\/jats:title>To explore the mineral features of dentin and cementum in hypoplastic Amelogenesis imperfecta AI<\/jats:styled-content> teeth.<\/jats:p><\/jats:sec>Materials and methods<\/jats:title>Forty\u2010four (44) teeth cleaned and free of caries were used: 20 control and 24 affected by hypoplastic amelogenesis imperfecta. Thirty\u2010two teeth were studied by pQCT<\/jats:styled-content>, cut in sections, and analyzed under microradiography, polarized light microscopy, and confocal Raman spectroscopy. Eight teeth were observed under scanning electron microscope. Four teeth were used for an X\u2010ray diffraction. The mineral density data were analyzed statistically with the Mann\u2013Whitney U<\/jats:italic> test, using GraphPad InStat software.<\/jats:p><\/jats:sec>Results<\/jats:title>Both coronal dentin and radicular dentin were less mineralized in AI<\/jats:styled-content> teeth when compared to control (respectively 6.2% and 6.8%; p\u00a0<\/jats:italic><\u00a0<\/jats:italic>.001). Root dentinal walls were thin and irregular, while the cellular cementum layers were thick, reaching sometimes the cervical region of the tooth. Regular dentinal tubules and sclerotic dentin areas were noticed. Partially tubular or cellular dysplastic dentin and hyper\u2010, normo\u2010, or hypomineralized areas were noticed in the inter\u2010radicular areas of hypoplastic AI<\/jats:styled-content> teeth. The main mineral component was carbonate hydroxyapatite as explored by Raman spectroscopy and X\u2010ray diffraction.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Dentin and cementum in hypoplastic AI<\/jats:styled-content> teeth are (i) hypomineralized, (ii) constituted of carbonate hydroxyapatite, and (iii) of non\u2010homogenous structure.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12724","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T19:41:54Z","timestamp":1501789314000},"page":"384-392","source":"Crossref","is-referenced-by-count":14,"title":["Mineral features of connective dental hard tissues in hypoplastic amelogenesis imperfecta"],"prefix":"10.1111","volume":"24","author":[{"given":"R","family":"Kammoun","sequence":"first","affiliation":[{"name":"Laboratory of Histology and Embryology Laboratory of Dento\u2010Facial, Clinical and Biological Approach (ABCDF) Faculty of Dental Medicine University of Monastir Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Behets","sequence":"additional","affiliation":[{"name":"P\u00f4le de Morphologie Institut de Recherche Exp\u00e9rimentale et Clinique Universit\u00e9 Catholique de Louvain Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Mansour","sequence":"additional","affiliation":[{"name":"Laboratory of Histology and Embryology Laboratory of Dento\u2010Facial, Clinical and Biological Approach (ABCDF) Faculty of Dental Medicine University of Monastir Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1460-8191","authenticated-orcid":false,"given":"S","family":"Ghoul\u2010Mazgar","sequence":"additional","affiliation":[{"name":"Laboratory of Histology and Embryology Laboratory of Dento\u2010Facial, Clinical and Biological Approach (ABCDF) Faculty of Dental Medicine University of Monastir Monastir Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.2003.00843.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016359309041152"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1515\/folmed-2016-0008"},{"key":"e_1_2_9_5_1","volume-title":"Oral Anatomy, histology and embryology","author":"Berkovitz B. 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