{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:49:26Z","timestamp":1779886166670,"version":"3.53.1"},"reference-count":61,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,28]],"date-time":"2017-09-28T00:00:00Z","timestamp":1506556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003758","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico do Maranh\u00e3o","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003758","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To estimate the association between sickle cell anaemia and trait with dental and jaw bone abnormalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Subjects (<jats:italic>n<\/jats:italic>\u00a0=\u00a0369) were allocated to three groups: sickle cell anaemia, trait and control. Dental shape, number, size and position and changes in pulp chamber, root and periapex were analysed by intra\u2010oral periapical radiographs. Integrity of lamina dura, quality of cancellous bone and bone trabeculation were also evaluated. Prevalence ratios (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>) were calculated (\u03b1\u00a0=\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sickle cell anaemia had higher prevalence (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>:8.31) and number of teeth (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>:13.40) with external resorption; higher number of teeth with pulp calcification; partial and total loss of lamina dura; and higher prevalence of changes in trabecular structure of maxilla (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>:6.45) and mandible (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>:5.34). Sickle cell trait showed higher prevalence (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>:1.26) and higher number of teeth (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>:1.98) with partial loss of lamina dura; higher number of teeth with hypercementosis, changes in shape, size, periapex, total loss of lamina dura; and higher prevalence of changes in mandibular trabecular bone (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>:1.43).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pulp calcification and external resorption of the root were the most frequent dental alterations in sickle cell anaemia group, while in trait was higher frequency of changes in shape, size, periapex and root. Jaw bone changes were most prevalent in both homozygous and heterozygous subjects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12742","type":"journal-article","created":{"date-parts":[[2017,8,21]],"date-time":"2017-08-21T02:42:38Z","timestamp":1503283358000},"page":"393-403","source":"Crossref","is-referenced-by-count":19,"title":["Association of sickle cell haemoglobinopathies with dental and jaw bone abnormalities"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8730-8600","authenticated-orcid":false,"given":"SFC","family":"Souza","sequence":"first","affiliation":[{"name":"Department of Dentistry Federal University of Maranh\u00e3o  S\u00e3o Lu\u0131s Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HLCC","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Postgraduate Dentistry Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u0131s Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CPS","family":"Costa","sequence":"additional","affiliation":[{"name":"Postgraduate Dentistry Program Federal University of Maranh\u00e3o  S\u00e3o Lu\u0131s Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EBAF","family":"Thomaz","sequence":"additional","affiliation":[{"name":"Department of Public Health Federal University of Maranh\u00e3o  S\u00e3o Lu\u0131s Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,9,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10005-1301"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2005.05476.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2005.06.027"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.100032"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0011-8532(22)00661-9","article-title":"Dental variation among populations. An anthropologic view","volume":"19","author":"Bailit H. L.","year":"1975","journal-title":"Dental Clinics of North America"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.1995.tb00319.x"},{"key":"e_1_2_9_8_1","unstructured":"Brazilian Market Research Association(2015).Changes in the application of the Brazilian Criteria in force as of January 1 st."},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12342"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9416(57)90201-4"},{"key":"e_1_2_9_11_1","first-page":"73","volume-title":"Epidemiology for the uninitiated","author":"Coggon D.","year":"2003"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2010.526838"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/1807-3107BOR-2015.vol29.0017","article-title":"Is sickle cell anemia a risk factor for severe dental malocclusion?","volume":"29","author":"Costa C. P. S.","year":"2015","journal-title":"Brazilian Oral Research"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.5581\/1516-8484.20120016"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.10.024"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2008.03.007"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2004.00853.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1179\/bjo.17.2.115"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-0707.108216"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107BOR-2016.vol30.0060"},{"key":"e_1_2_9_21_1","first-page":"159","article-title":"Sickle cell anemia: A review for the pediatric dentist","volume":"29","author":"Fonseca M.","year":"2007","journal-title":"Pediatric Dentistry"},{"key":"e_1_2_9_22_1","first-page":"92","article-title":"Buccal manifestations of sickle cell anemia and their implications in dentistry services (in portuguese)","volume":"43","author":"Franco B. D. M.","year":"2007","journal-title":"Arquivos em Odontologia"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-9657.2003.00192.x"},{"key":"e_1_2_9_24_1","first-page":"355","article-title":"Sickle cell disease and trait: An increase in trabecular spacing, a case study","volume":"78","author":"Gillis M. V.","year":"2004","journal-title":"Journal of Dental Hygiene"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.22271"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(70)90383-X"},{"key":"e_1_2_9_27_1","first-page":"556","article-title":"Prevalence of fused and geminated teeth in Jordanian adults","volume":"35","author":"Hamasha A. A.\u2010H.","year":"2004","journal-title":"Quintessence International"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016358109162264"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e318265b146"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21475"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(96)80261-7"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2010.1.418"},{"key":"e_1_2_9_33_1","first-page":"896","article-title":"Natural history and distribution of bone and bone marrow infarction in sickle hemoglobinopathies","volume":"43","author":"Kim S. K.","year":"2002","journal-title":"The Journal of Nuclear Medicine"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070578"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20691"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(74)90146-7"},{"key":"e_1_2_9_38_1","first-page":"9","article-title":"Tooth resorption","volume":"30","author":"Ne R. F.","year":"1999","journal-title":"Quintessence International"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2011.00195.x"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-011-0577-0"},{"key":"e_1_2_9_41_1","first-page":"49","volume-title":"Oral and maxillofacial pathology","author":"Neville B.","year":"2015"},{"key":"e_1_2_9_42_1","first-page":"111","volume-title":"Oral and maxillofacial pathology","author":"Neville B.","year":"2015"},{"key":"e_1_2_9_43_1","first-page":"572","volume-title":"Oral and maxillofacial pathology","author":"Neville B.","year":"2015"},{"key":"e_1_2_9_44_1","first-page":"49","volume-title":"Oral and maxillofacial pathology","author":"Neville B.","year":"2015"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.1996.tb00218.x"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2005.00648.x"},{"key":"e_1_2_9_47_1","first-page":"321","article-title":"Anthropometric findings in Nigerian children with sickle cell disease","volume":"24","author":"Oredugba F. A.","year":"2002","journal-title":"Pediatric Dentistry"},{"key":"e_1_2_9_48_1","first-page":"316","article-title":"Managing the dental patient with sickle cell anemia : A review of the literature","volume":"12","author":"Sams D. R.","year":"1990","journal-title":"Pediatric Dentistry"},{"key":"e_1_2_9_49_1","first-page":"32","article-title":"Radiographic bone changes in sickle cell anemia","volume":"32","author":"Sanger R. G.","year":"1977","journal-title":"Journal of Oral Medicine"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-008-0212-x"},{"key":"e_1_2_9_51_1","first-page":"262","article-title":"Studies of permanent tooth anomalies in 7,886 Canadian individuals. I: Impacted teeth","volume":"44","author":"Shah R. M.","year":"1978","journal-title":"Dental Journal"},{"key":"e_1_2_9_52_1","first-page":"1","article-title":"Hypercementosis: A rare finding in a patient with systemic lupus erythematosus","volume":"26","author":"Shoor H.","year":"2014","journal-title":"Case Reports"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(91)90184-E"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(66)90221-4"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2008.157"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2009.10"},{"key":"e_1_2_9_57_1","first-page":"204","article-title":"The role of evidence\u2010based dentistry","volume":"67","author":"Sutherland S.","year":"2001","journal-title":"Journal\/Canadian Dental Association. Journal de l'Association Dentaire Canadienne"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.1995.tb00469.x"},{"key":"e_1_2_9_59_1","first-page":"395","article-title":"Prevalence of dental anomalies in orthodontic patients","volume":"43","author":"Thongudomporn U.","year":"1998","journal-title":"Australian Dental Journal"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.12.020"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.dmfr.4600516"},{"key":"e_1_2_9_62_1","first-page":"e485","article-title":"Prevalence and distribution of selected dental anomalies among saudi children in Abha, Saudi Arabia","volume":"8","author":"Yassin S. M.","year":"2016","journal-title":"Journal of Clinical and Experimental Dentistry"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fodi.12742","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.12742","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T23:38:34Z","timestamp":1695685114000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.12742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,28]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1111\/odi.12742"],"URL":"https:\/\/doi.org\/10.1111\/odi.12742","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,28]]}}}