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The origin of the name means \u201cto bend forward or become contorted,\u201d in reference to the posture adopted by patients due to the joint pain that occurs during the infection. Epidemiology data suggest that by the end of 2015, about 1.6 million people had been infected with\n                    <jats:styled-content style=\"fixed-case\">CHIKV<\/jats:styled-content>\n                    . The acute period of the disease is characterized by high fever, myalgia, joint pain, and severe and disabling polyarthritis, sometimes accompanied by headache, backache, and maculopapular rash, predominantly on the thorax. Around half of the patients will progress to the subacute and chronic phases, that is manifested by persistent polyarthritis\/polyarthralgia, accompanied by morning stiffness and fatigue, which could remain for years. Oral features may include gingivitis possibly as a consequence of arthralgia of the hands leading to limited oral health measures as well as burning sensation and oral mucosal ulceration. Treatment in the acute phase includes acetaminophen, and weak opioids (tramadol or codeine) should be used in cases of severe or refractory pain. For patients who have progressed to the subacute stage and who have not had notable benefit from common analgesics or opioids,\n                    <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>\n                    s, or adjunctive pain medications (anticonvulsants or antidepressants) may be of benefit. In patients with moderate\u2010to\u2010severe musculoskeletal pain or in those who cannot be given or tolerate\n                    <jats:styled-content style=\"fixed-case\">NSIAD<\/jats:styled-content>\n                    s or opiates, prednisolone should be prescribed.\n                  <\/jats:p>","DOI":"10.1111\/odi.12777","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T09:30:50Z","timestamp":1519637450000},"page":"233-237","source":"Crossref","is-referenced-by-count":6,"title":["Chikungunya fever: General and oral healthcare implications"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8303-2291","authenticated-orcid":false,"given":"JC","family":"Leao","sequence":"first","affiliation":[{"name":"Oral Medicine Unit Departamento de Cl\u00ednica e Odontologia Preventiva Universidade Federal de Pernambuco Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CDL","family":"Marques","sequence":"additional","affiliation":[{"name":"Rheumatology Unit Hospital das Cl\u00ednicas Universidade Federal de Pernambuco Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ALBP","family":"Duarte","sequence":"additional","affiliation":[{"name":"Rheumatology Unit Hospital das Cl\u00ednicas Universidade Federal de Pernambuco Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OP","family":"de Almeida","sequence":"additional","affiliation":[{"name":"\u00c1rea de Patologia Departamento de Diagn\u00f3stico Oral Facldade de Odontologia de Piracicaba Universidade Estadual de Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Porter","sequence":"additional","affiliation":[{"name":"UCL Eastman Dental Institute Oral Theme of the UCL\/UCLH NIHR Biomedical Research Centre London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4979-4318","authenticated-orcid":false,"given":"LA","family":"Gueiros","sequence":"additional","affiliation":[{"name":"Oral Medicine Unit Departamento de Cl\u00ednica e Odontologia Preventiva Universidade Federal de Pernambuco Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2016.02.033"},{"key":"e_1_2_8_3_1","first-page":"973516","article-title":"Molecular mechanisms involved in the pathogenesis of alphavirus\u2010induced arthritis","volume":"2013","author":"Assuncao\u2010Miranda I.","year":"2010","journal-title":"Biomedical Research International"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.60356"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.82483"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/590003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/517537"},{"key":"e_1_2_8_8_1","first-page":"1","article-title":"Monitoramento dos casos de dengue, febre de chikungunya e febre pelo v\u00edrus Zika at\u00e9 a Semana Epidemiol\u00f3gica 19 (2017)","volume":"48","author":"Brazil","year":"2017","journal-title":"Brazilian Health Ministry"},{"key":"e_1_2_8_9_1","unstructured":"Brazilian Medical Council(2015).Febre de Chikungunya \u2013 Manejo Cl\u00ednico. 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