{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T01:43:13Z","timestamp":1776649393249,"version":"3.51.2"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T00:00:00Z","timestamp":1518048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the incidence and magnitude of bacteremia after dental extraction and supragingival scaling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and methods<\/jats:title><jats:p>Blood samples were taken before and 5 and 30\u00a0min after dental extraction and supragingival scaling from individuals at high (<jats:italic>n<\/jats:italic>\u00a0=\u00a044) or negligible risk (<jats:italic>n<\/jats:italic>\u00a0=\u00a051) for infective endocarditis. The former received prophylactic antibiotic therapy. Samples were subjected to aerobic and anaerobic culture and quantitative real\u2010time polymerase chain reaction to determine the incidence of bacteremia and total bacterial levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients who did not receive prophylactic antibiotic therapy had a higher incidence of positive blood cultures (30% 5\u00a0min after extraction) than patients who received prophylactic antibiotic therapy (0% 5\u00a0min after extraction; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.01). Molecular analysis did not reveal significant differences in the incidence or magnitude of bacteremia between the two patient groups either 5 or 30\u00a0min after each of the procedures evaluated. Extraction was associated with higher incidence of bacteremia than supragingival scaling by blood culture (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.03) and molecular analysis (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Molecular methods revealed that dental extraction and supragingival scaling were associated with similar incidence of bacteremia in groups receiving or not prophylactic antibiotic therapy. However, blood culture revealed that antibiotic therapy reduced viable cultivable bacteria in the bloodstream in the extraction group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.12792","type":"journal-article","created":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T02:22:56Z","timestamp":1507602176000},"page":"657-663","source":"Crossref","is-referenced-by-count":14,"title":["Bacteremia after supragingival scaling and dental extraction: Culture and molecular analyses"],"prefix":"10.1111","volume":"24","author":[{"given":"LC","family":"Reis","sequence":"first","affiliation":[{"name":"National Institute of Cardiology  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"IN","family":"R\u00f4\u00e7as","sequence":"additional","affiliation":[{"name":"Department of Endodontics Est\u00e1cio de S\u00e1 University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"JF","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Department of Endodontics Est\u00e1cio de S\u00e1 University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"de Uzeda","sequence":"additional","affiliation":[{"name":"Department of Endodontics Est\u00e1cio de S\u00e1 University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VS","family":"Lacerda","sequence":"additional","affiliation":[{"name":"National Institute of Cardiology  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RMCP","family":"Domingues","sequence":"additional","affiliation":[{"name":"Institute of Microbiology Paulo de G\u00f3es Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KR","family":"Miranda","sequence":"additional","affiliation":[{"name":"Institute of Microbiology Paulo de G\u00f3es Federal University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2263-4261","authenticated-orcid":false,"given":"RM","family":"Saraiva","sequence":"additional","affiliation":[{"name":"Evandro Chagas National Institute of Infectious Diseases Oswaldo Cruz Foundation  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.9.3334-3340.2002"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02004-07"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp008"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124249"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcli.2011.03.029"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057782"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118357"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01717.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.02.029"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00924.x"},{"key":"e_1_2_8_12_1","first-page":"1","article-title":"Dissemination of periodontal pathogens in the bloodstream after periodontal procedures: A systematic review","volume":"9","author":"Horliana A. 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