{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T07:46:18Z","timestamp":1778139978455,"version":"3.51.4"},"reference-count":8,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T00:00:00Z","timestamp":1560988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We hypothesized that the extravasation of saliva from damaged ducts with lymphocytic infiltration in patients with Sj\u00f6gren's syndrome causes ranulas. There are too many uncertainties to support this hypothesis. The aim of this study was to investigate whether there is an association between Sj\u00f6gren's syndrome and ranulas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We observed three cases of patients with ranulas who were also diagnosed with Sj\u00f6gren's syndrome at the same facility. These cases led to the question of whether there are other such cases, and thus, an exhaustive literature search was conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three cases in two case reports of mucocele of the floor of the mouth associated with adult Sj\u00f6gren's syndrome were noted. Including our cases, until now, there have been six cases of ranula with adult Sj\u00f6gren's syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It could be useful to investigate whether patients presenting with a ranula are also affected by Sj\u00f6gren's syndrome and, conversely, investigate patients with Sj\u00f6gren's syndrome longitudinally to see whether they develop ranulas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.13130","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T12:39:00Z","timestamp":1559133540000},"page":"1664-1667","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Sj\u00f6gren\u2019s syndrome and ranula development"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1339-9199","authenticated-orcid":false,"given":"Kazumichi","family":"Sato","sequence":"first","affiliation":[{"name":"Department of Oral Medicine, Oral and Maxillofacial Surgery Tokyo Dental College Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshifumi","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Oral and Maxillofacial Surgery Tokyo Dental College Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiko","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Oral and Maxillofacial Surgery Tokyo Dental College Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Shibui","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Oral and Maxillofacial Surgery Tokyo Dental College Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Division of Surgical Pathology, Clinical Laboratory, Ichikawa General Hospital Tokyo Dental College Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Radiology The Jikei University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Oral and Maxillofacial Surgery Tokyo Dental College Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2010.01197.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-017-0501-3"},{"key":"e_1_2_7_4_1","first-page":"227","volume-title":"Surgical pathology of the mouth and jaws","author":"Cawson R. 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