{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T17:06:20Z","timestamp":1774026380828,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T00:00:00Z","timestamp":1578873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study investigated the predictive role of pretreatment swallowing function and surgical factors on postoperative and nosocomial lower respiratory tract infections (PN\u2010LRTIs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and methods<\/jats:title><jats:p>A retrospective study for predicting PN\u2010LRTIs from January 2017 to December 2018 at Hospital of Stomatology, Sun Yat\u2010sen University. Patients who were newly diagnosed with tongue squamous cell carcinoma (TSCC) were enrolled. Presurgical swallowing function was assessed using water swallow test (WST) and the M.D. Anderson Dysphagia Inventory (MDADI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 83 patients were recruited to the study. Of which 54 were men (65.1%) and 29 were women (34.9%), with the mean age of 51\u00a0years old. Thirteen (15.7%) developed PN\u2010LRTIs. On univariate analysis, the outcomes of WST, the MDADI scores, T stage, tongue resection range, operative time, segmental mandibulectomy, and type of neck dissection exhibited a statistical significance (<jats:italic>p\u00a0&lt;\u00a0<\/jats:italic>.05). On multivariate analysis, abnormal group of WST (odds ratio [OR], 15.88; 95% CI, 2.13\u2013118.64) and total glossectomy (OR, 12.20; 95% CI, 2.01\u201368.32) was demonstrated to be independent risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The WST together with the resection range of tongue can predict the postoperative risk of PN\u2010LRTIs collaboratively. Clinically, preventive measures and intensified care should be taken for patients with abnormal WST outcome before surgery and management of total glossectomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.13270","type":"journal-article","created":{"date-parts":[[2019,12,30]],"date-time":"2019-12-30T10:53:49Z","timestamp":1577703229000},"page":"537-546","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prediction of postoperative lower respiratory tract infections in tongue cancer patients based on pretreatment swallowing function"],"prefix":"10.1111","volume":"26","author":[{"given":"Wei","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Guangdong Provincial Key Laboratory of Stomatology Guanghua School of Stomatology Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Guangdong Provincial Key Laboratory of Stomatology Guanghua School of Stomatology Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunqing","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine The Third Affiliated Hospital Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanzi","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Guangdong Provincial Key Laboratory of Stomatology Guanghua School of Stomatology Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yudong","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Guangdong Provincial Key Laboratory of Stomatology Guanghua School of Stomatology Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Guangdong Provincial Key Laboratory of Stomatology Guanghua School of Stomatology Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujie","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Guangdong Provincial Key Laboratory of Stomatology Guanghua School of Stomatology Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0338-6661","authenticated-orcid":false,"given":"Guiqing","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Guangdong Provincial Key Laboratory of Stomatology Guanghua School of Stomatology Sun Yat\u2010sen University Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,13]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"870","article-title":"The development and validation of a dysphagia\u2010specific quality\u2010of\u2010life questionnaire for patients with head and neck cancer","volume":"127","author":"Chen A.","year":"2001","journal-title":"Archives of Otolaryngology \u2013 Head and Neck Surgery"},{"key":"e_1_2_8_3_1","first-page":"870","article-title":"The development and validation of a dysphagia\u2010specific quality\u2010of\u2010life questionnaire for patients with head and neck cancer: The M. 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