{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:00:50Z","timestamp":1792623650608,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T00:00:00Z","timestamp":1583193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To analyze the location and degree of parotid ductal abnormalities associated with Sjogren's syndrome (SS) and to correlate findings with the duration of the disease. To develop a classification system based on contemporary sialography techniques and employ the system to grade findings on sialograms. To assess the role for therapeutic intervention in patients with SS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective chart review of a consecutive series of 337 sialograms done by the senior investigator over a 10\u2010year period identified 26 sialograms in patients who met the criteria for SS as defined by the American\u2010European Consensus Group (2002). A classification system was developed to grade the degree of ductal abnormalities identified on the sialograms. Individual, initial blinded review of these sialograms was performed by two head and neck radiologists to identify and grade abnormalities. Radiographic findings were correlated with patient history including symptom duration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All patients with SS had stenoses within the ductal system. About 73.1% of patients had stenoses in each branch of the ductal system (primary, secondary, and tertiary ducts). In 19% of patients, the main duct was of normal caliber despite the presence of stenosis in the more proximal ducts (secondary and tertiary ducts). Peripheral (proximal) duct dilation was characterized among those affected in patterns classified as destructive (34.6%), cavitary (26.9%), globular (11.5%), or punctate (11.5%). A statistically significant positive correlation (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.0360) was identified between symptom duration and degree of main ductal stenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sialography may be useful to objectively assess the degree of parotid ductal damage in SS employing a newly proposed classification system. This assessment may assist clinicians in tailoring management to selectively include ductal dilation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.13298","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T11:08:58Z","timestamp":1581073738000},"page":"912-919","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Sialographic analysis of parotid ductal abnormalities associated with Sjogren's syndrome"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5967-6054","authenticated-orcid":false,"given":"Megan J.","family":"Foggia","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery University of Iowa Hospitals and Clinics Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Peterson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery University of Iowa Hospitals and Clinics Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Maley","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Iowa Hospitals and Clinics Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Policeni","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Iowa Hospitals and Clinics Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry T.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head &amp; Neck Surgery University of Iowa Hospitals and Clinics Iowa City IA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12736"},{"issue":"3","key":"e_1_2_9_3_1","first-page":"215","article-title":"Imaging in primary Sjogren's syndrome: The 'obsolete and the new'","volume":"112","author":"Baldini C.","year":"2018","journal-title":"Clinical and Experimental Rheumatology"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(73)90273-9"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348945606500201"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-018-4153-8"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/014556131509400610"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2586(200005)11:5<518::AID-JMRI7>3.0.CO;2-5"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12512"},{"issue":"9","key":"e_1_2_9_10_1","first-page":"1485","article-title":"Comparative study of MR sialography and digital subtraction sialography for benign salivary gland disorders","volume":"23","author":"Kalinowski M.","year":"2002","journal-title":"AJNR. 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