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The Methodological Quality and Synthesis of Case Series and Case Reports in association with the Case Series and Prevalence Studies from the Joanna Briggs Institute critical appraisal tools were used for the risk of bias. We followed the PRISMA checklist guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty\u2010four studies reporting GF as an oral manifestation of a syndrome were identified in this review. Enamel renal syndrome was the most frequently reported syndrome with GF, represented by 54 individuals in 19 studies, followed by Zimmermann\u2013Laband syndrome with 24 individuals in 15 studies and Costello syndrome, which was presented in a case series study with 41 individuals. Among reported cases, other clinical manifestations such as hypertrichosis, ectopic gingival calcification, and cherubism were described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results emphasize the need of systematic oro\u2010dental\u2010facial phenotyping for future descriptions as well as further molecular analysis in order to better understand the occurrence of syndromic GF.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.13369","type":"journal-article","created":{"date-parts":[[2020,4,26]],"date-time":"2020-04-26T08:00:40Z","timestamp":1587888040000},"page":"881-893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Syndromes with gingival fibromatosis: A systematic review"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0596-8267","authenticated-orcid":false,"given":"Cl\u00e1udio Rodrigues 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