{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T10:18:09Z","timestamp":1774952289721,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T00:00:00Z","timestamp":1598745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The immune reconstitution inflammatory syndrome (IRIS) is a rare acute complication presenting in people living with HIV (PLWH) within the first 6\u00a0months of starting combined antiretroviral therapy (cART). While there is relevant information about its pathogenesis and clinical spectrum, IRIS\u2010oral lesions (IRIS\u2010OLs) have been scarcely described. Thus, to establish the incidence and clinical characteristics of IRIS\u2010OLs, data from a cohort of 158 HIV individuals starting cART, followed for 6\u00a0months, were obtained retrospectively. IRIS\u2010OLs developed in 11.4% of the individuals, in a median time of 87.5\u00a0days, with oral candidiasis being the most frequent manifestation detected in eight individuals (5.1%). The study emphasizes the importance of the correct diagnosis and management of these lesions.<\/jats:p>","DOI":"10.1111\/odi.13402","type":"journal-article","created":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T20:46:57Z","timestamp":1598820417000},"page":"153-157","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical manifestations and risk factors for oral immune reconstitution inflammatory syndrome in Mexico"],"prefix":"10.1111","volume":"26","author":[{"given":"Itzel","family":"Castillejos\u2010Garc\u00eda","sequence":"first","affiliation":[{"name":"Oral Pathology and Medicine Master Universidad Aut\u00f3noma Metropolitana\u2010Xochimilco Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Velia","family":"Ram\u00edrez\u2010Amador","sequence":"additional","affiliation":[{"name":"Oral Pathology and Medicine Master Universidad Aut\u00f3noma Metropolitana\u2010Xochimilco Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"G\u00f3mez\u2010Mej\u00eda","sequence":"additional","affiliation":[{"name":"Oral Pathology and Medicine Master Universidad Aut\u00f3noma Metropolitana\u2010Xochimilco Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florentino","family":"Badial\u2010Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Especializada Condesa Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Anaya\u2010Saavedra","sequence":"additional","affiliation":[{"name":"Oral Pathology and Medicine Master Universidad Aut\u00f3noma Metropolitana\u2010Xochimilco Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,30]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Immune reconstitution inflammatory syndrome generic criteria","author":"AIDS Clinical Trials Group Network [ACTG]","year":"2009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-009-9217-5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2712"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2217\/17520363.2.4.349"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12019"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jicd.12351"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000131375.21070.06"},{"issue":"2","key":"e_1_2_7_9_1","first-page":"E85","article-title":"Oral lesions and immune reconstitution syndrome in HIV+\/AIDS patients receiving highly active antiretroviral therapy. Epidemiological evidence","volume":"13","author":"Gaitan L. C.","year":"2008","journal-title":"Medicina Oral, Patologia Oral Y Cirugia Bucal"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011416"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040623"},{"key":"e_1_2_7_12_1","volume-title":"Immune reconstitution inflammatory syndrome (IRIS). Tag archives: HIV\u2010associated IRIS","author":"Hofffmann C.","year":"2011"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e328302ebbb"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-09-380840"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e3181594c8c"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1086\/595006"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70026-8"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283511e91"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1086\/657082"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2007.007261"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.02.035"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2008.008351"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511400080"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1086\/503903"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2000.290708.x"},{"issue":"2","key":"e_1_2_7_26_1","first-page":"67","article-title":"The immune reconstitution inflammatory syndrome","volume":"5","author":"Shelburne S. A.","year":"2003","journal-title":"AIDS Reviews"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki444"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000161769.06158.8a"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2009.00749.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511399915"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/2325957417702485"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12981-017-0156-9"},{"key":"e_1_2_7_33_1","first-page":"49","article-title":"Immune reconstitution inflammatory syndrome in HIV\u2010infected patients","volume":"7","author":"Walker N. F.","year":"2015","journal-title":"HIV\/AIDS (Auckland, New Zealand)"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.13402","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/odi.13402","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.13402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T21:24:29Z","timestamp":1693949069000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.13402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,30]]},"references-count":32,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/odi.13402"],"URL":"https:\/\/doi.org\/10.1111\/odi.13402","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,30]]},"assertion":[{"value":"2020-08-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}