{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T01:34:42Z","timestamp":1791855282569,"version":"4.3.4"},"reference-count":90,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Capnocytophaga<\/jats:italic> spp. are commensal bacteria of the oral cavity and constitute a genus of the core microbiome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This genus is responsible for many local and systemic conditions in both the immunocompetent and immunocompromised patients, but its beneficial or deleterious role in the microbiota has been little explored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Online databases were used to identify papers published from 1999 to 2019 based on next\u2010generation sequencing (NGS) data to study comparative trials. Work using other identification methods, case reports, reviews, and non\u2010comparative clinical trials was excluded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results and conclusion<\/jats:title><jats:p>We selected 42 papers from among 668 publications. They showed a link between the abundance of <jats:italic>Capnocytophaga<\/jats:italic> spp. in the oral microbiota and various local pathologies (higher for gingivitis and halitosis; lower in active smokers, etc.) or systemic diseases (higher for cancer and carcinomas, IgA nephropathy, etc.). After discussing the limits inherent to the NGS techniques, we present several technical and biological hypotheses to explain the diversity of results observed between studies, as well as the links between the higher or lower abundance of <jats:italic>Capnocytophaga<\/jats:italic> spp and the appearance of local or systemic conditions and diseases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.13573","type":"journal-article","created":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T09:33:48Z","timestamp":1596274428000},"page":"1621-1630","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Screening for prevalence and abundance of <i>Capnocytophaga spp<\/i> by analyzing NGS data: A scoping review"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4057-9876","authenticated-orcid":false,"given":"Anne","family":"Jolivet\u2010Gougeon","sequence":"first","affiliation":[{"name":"INSERM, INRAE, CHU Rennes Institut NUMECAN (Nutrition Metabolisms and Cancer) Univ Rennes Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Bonnaure\u2010Mallet","sequence":"additional","affiliation":[{"name":"INSERM, INRAE, CHU Rennes Institut NUMECAN (Nutrition Metabolisms and Cancer) Univ Rennes Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00347"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/20002297.2018.1557986"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb00546.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.120592"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12087"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12470"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/ejd.ejd_309_16"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000490029"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00840"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2012.01498.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1988.tb01365.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3130607"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8163591"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-017-0252-z"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2014.10.003"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkt350"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx119"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(16)30086-3"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.10.097"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-018-1274-9"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19123720"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.32152"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa4972"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-1842.2009.00848.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034518805739"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01232-10"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1996.tb08108.x"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056343"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijos.2013.15"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1994.tb00284.x"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00248-014-0372-y"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515609554"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.11.3186-3188.2000"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2008.00824.x"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-5-32"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034519889015"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms7010020"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000557"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2018.12.083"},{"issue":"3","key":"e_1_2_9_41_1","first-page":"304","article-title":"Oral microbiological diversity in patients with salivary adenoid cystic carcinoma","volume":"37","author":"Liu X.","year":"2019","journal-title":"Hua Xi Kou Qiang Yi Xue Za Zhi"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-3-27"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.02042-14"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0185274"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1983.54.7.420"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-48768-z"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-47-12-1087"},{"issue":"22","key":"e_1_2_9_48_1","article-title":"Distribution of dipeptidyl peptidase (DPP) 4, DPP5, DPP7 and DPP11 in human oral microbiota\u2010potent biomarkers indicating presence of periodontopathic bacteria","volume":"365","author":"Ohara\u2010Nemoto Y.","year":"2018","journal-title":"FEMS Microbiology Letters"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-019-01790-1"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515583531"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.12.3770-3783.2001"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-64402012000400017"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2013.130273"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034518767118"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12597"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.1605.05012"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.02061.x"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16173184"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1080\/20002297.2019.1633194"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1088\/1752-7163\/aa7c24"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034510377203"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0236"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2006.00697.x"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(98)00062-1"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02419.x"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1099\/13500872-142-8-2161"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2016.07.020"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.job.2019.03.003"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12159"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2011.01409.x"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2016.08.005"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-014-0250-2"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2015.01.011"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0850"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2016.04.007"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/1253727"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-019-05084-6"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2018.02.008"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009293500209"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2016.37"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.4458"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-019-0947-6"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01145"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089269"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2018.11.051"},{"issue":"10","key":"e_1_2_9_86_1","first-page":"3111","article-title":"Discovery and validation of potential bacterial biomarkers for lung cancer","volume":"5","author":"Yan X.","year":"2015","journal-title":"American Journal of Cancer Research"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.17706.1"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1997.tb00535.x"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-9-259"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2015.00055"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00476"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fodi.13573","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.13573","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/odi.13573","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.13573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:41:21Z","timestamp":1693356081000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.13573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,31]]},"references-count":90,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1111\/odi.13573"],"URL":"https:\/\/doi.org\/10.1111\/odi.13573","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,31]]},"assertion":[{"value":"2020-03-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}