{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T20:45:44Z","timestamp":1773089144021,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T00:00:00Z","timestamp":1603238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purpose of this study was to evaluate the occurrence rate of drug\u2010induced gingival overgrowth (DIGO) in patients treated with angiotensin\u2010converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and calcium channel blockers (CCBs) such as amlodipine, lercanidipine, and benidipine, as well as to assess the relationship of those mentioned above with medication variables and oral hygiene.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sociodemographic details, DIGO, and clinical periodontal parameters were obtained from one hundred and thirty\u2010one patients receiving ACE inhibitors, ARBs, and CCBs for a period of at least 2\u00a0years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The occurrence rate of DIGO was 19.6% in patients using CCB, 12.5% in the ARB group, and 7.5% in the ACE inhibitor group. In a subgroup analysis of CCBs, DIGO was found to be 31.8% in the amlodipine group, 13.3% in the lercanidipine group, and 7.1% in the benidipine group. While there was a significant relationship between amlodipine drug dosage and DIGO, no association was found between the duration of therapy and DIGO in all CCB subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There was no difference between the groups in terms of DIGO. Duration of therapy and drug dosage did not affect the severity of DIGO in both ACE inhibitors and ARB groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13655","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T17:26:12Z","timestamp":1601400372000},"page":"1313-1319","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Influence of different anti\u2010hypertensive drugs on gingival overgrowth: A cross\u2010sectional study in a Turkish population"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4205-861X","authenticated-orcid":false,"given":"G\u00fclbahar","family":"Ustao\u011flu","sequence":"first","affiliation":[{"name":"Department of Periodontology Bolu Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3893-5376","authenticated-orcid":false,"given":"Emrah","family":"Erdal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Bolu Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7366-5666","authenticated-orcid":false,"given":"Zeynep","family":"Kara\u015f","sequence":"additional","affiliation":[{"name":"Department of Periodontology Bolu Abant Izzet Baysal University Bolu Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4236\/ojst.2014.44025"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2012.01878.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.10.1424"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.1.63"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12426"},{"issue":"7","key":"e_1_2_10_7_1","first-page":"467","article-title":"New clinical index for drug\u2010induced gingival overgrowth","volume":"30","author":"Ingles E.","year":"1999","journal-title":"Quintessence International"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1997.68.7.676"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2011.00603.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309011240"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4065\/73.12.1196"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.025950"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.31729\/jnma.232"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12551"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2012.04.002"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb02072.x"},{"issue":"1","key":"e_1_2_10_17_1","first-page":"28","article-title":"Drug utilisation among older inpatients in a teaching hospital in Western Nepal","volume":"51","author":"Shankar P. 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