{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:53:53Z","timestamp":1772160833130,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:00:00Z","timestamp":1607731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic periodontitis is the most common form of periodontitis. Several immune and inflammatory factors responsible for periodontal destruction have been found in gingival crevicular fluid (GCF). The current study was conducted to determine the correlation between mucin and alpha\u2010amylase protein values in GCF with chronic periodontitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Forty\u2010five patients with moderate\u2010to\u2010severe chronic periodontitis were selected. Samples of GCF were taken from a specific part of a single root tooth and placed in a closed test tube containing phosphate\u2010buffered saline (PBS) (pH\u00a0=\u00a07). Sampling was done again after one month. Pre\u2010 and post\u2010treatment samples were analyzed for measuring the levels of mucin and alpha\u2010amylase proteins.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Paired\n                      <jats:italic>t<\/jats:italic>\n                      test results for these two variables showed that the difference between mucin and alpha\u2010amylase levels before and after treatment is significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The level of both mucin and alpha\u2010amylase in GCF in patients with chronic periodontitis was higher than that of patients who have recovered successfully; and evaluating the values of these two markers could be used to determine the activity of the periodontal disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13740","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T03:58:43Z","timestamp":1606795123000},"page":"210-215","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Assessment of mucin and alpha\u2010amylase levels in gingival crevicular fluid of chronic periodontitis patients"],"prefix":"10.1111","volume":"28","author":[{"given":"Bardia","family":"Vadiati Saberi","sequence":"first","affiliation":[{"name":"Department of Periodontology Guilan University of Medical Sciences Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farouq","family":"Yousefi","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Guilan University of Medical Sciences Rasht Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5263-9397","authenticated-orcid":false,"given":"Tooba","family":"Yousefi","sequence":"additional","affiliation":[{"name":"Cellular and Molecular Biology Research Center (CMBRC) Health Research Institute Babol University of Medical Sciences Babol Iran"},{"name":"Department of Clinical Biochemistry Babol University of Medical Sciences Babol Iran"},{"name":"Student Research Committee Babol University of Medical Sciences Babol Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1344-9344","authenticated-orcid":false,"given":"Durdi","family":"Qujeq","sequence":"additional","affiliation":[{"name":"Cellular and Molecular Biology Research Center (CMBRC) Health Research Institute Babol University of Medical Sciences Babol Iran"},{"name":"Department of Clinical Biochemistry Babol University of Medical Sciences Babol Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720140458"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100070"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12107"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12154"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2018.1396876"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0757.2003.03110.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2014.05.003"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.140520"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2012.01500.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0765.2003.00653.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2010.02.018"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2004.04.003"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1384.008"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.100565"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511401405"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2009.01140.x"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12194"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1997.2.1.123"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12670"},{"key":"e_1_2_11_21_1","first-page":"617","volume-title":"Carranza's Clinical Periodontology","author":"Newman M. 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