{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:49:32Z","timestamp":1788288572145,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,19]],"date-time":"2020-12-19T00:00:00Z","timestamp":1608336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the subjective effectiveness of oilpulling on medication\u2010induced xerostomia with regard to symptom relief, quality of life, taste, mucosal moisture and oral parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      In a randomized, single\u2010blind, crossover trial in participants with medication\u2010induced xerostomia (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a026; mean age 64.71 (standard deviation (\n                      <jats:italic>SD<\/jats:italic>\n                      ) 15.60) years), we investigated oilpulling efficacy (sunflower oil) versus mineral water after one\u2010week use. Xerostomic burden (visual analogue scale, VAS), symptom relief and oral examinations (gingivitis index, plaque index, whole stimulated and unstimulated salivation rates) were investigated at baseline and the end of the follow\u2010up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Oilpulling reduced the xerostomic burden (baseline value 6.46 (\n                      <jats:italic>SD<\/jats:italic>\n                      1.80), decreasing to 4.93 (\n                      <jats:italic>SD<\/jats:italic>\n                      2.97)) (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.003), without difference between oil versus water (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.067). Baseline values for water were 6.08 (\n                      <jats:italic>SD<\/jats:italic>\n                      2.17) decreasing to 5.72 (\n                      <jats:italic>SD<\/jats:italic>\n                      2.17) (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.124). Compared to water, oil made swallowing easier (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.031), caused a pleasant mouthfeel (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.031) and caused less waking up at night (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.031). Effectiveness (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.002) and duration (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.007) of symptom relief showed differences between products in favour of oil.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Oil pulling alleviated the overall xerostomic burden. In the comparison between oil and water, no difference regarding symptom relief could be shown. Patients should be informed of possibilities and limitations of oilpulling as inexpensive and easy\u2010to\u2010obtain alternative to commercially available products for short\u2010term symptom relief.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13752","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T05:51:20Z","timestamp":1607752280000},"page":"373-383","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Oil pulling to relieve medication\u2010induced xerostomia: A randomized, single\u2010blind, crossover trial"],"prefix":"10.1111","volume":"28","author":[{"given":"Lena","family":"Ludwar","sequence":"first","affiliation":[{"name":"Centre of Dental Medicine Department of Operative Dentistry and Periodontology University of Cologne K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilke","family":"Mannel","sequence":"additional","affiliation":[{"name":"Centre of Dental Medicine Department of Operative Dentistry and Periodontology University of Cologne K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Hamacher","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and University Hospital Cologne Institute of Medical Statistics and Computational Biology University of Cologne K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Johannes","family":"Noack","sequence":"additional","affiliation":[{"name":"Centre of Dental Medicine Department of Operative Dentistry and Periodontology University of Cologne K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0169-2582","authenticated-orcid":false,"given":"Anna Greta","family":"Barbe","sequence":"additional","affiliation":[{"name":"Centre of Dental Medicine Department of Operative Dentistry and Periodontology University of Cologne K\u00f6ln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.01.012"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.49067"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-4388.40315"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.79971"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb00126.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-018-0588-5"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13105"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2096-0"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2096-0"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2013.860621"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(01)00003-6"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.5005\/jcdp-9-3-72"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-007-0300-5"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(98)00109-2"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.1992.tb00401.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2009.00632.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005200000148"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016359609003557"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016359409029032"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2013.776701"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-015-0134-8"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.1995.tb00125.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309011240"},{"issue":"9","key":"e_1_2_9_25_1","first-page":"ZC08","article-title":"Comparative evaluation of antiplaque efficacy of coconut oil pulling and a placebo. 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