{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T10:15:04Z","timestamp":1784542504831,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T00:00:00Z","timestamp":1615248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Neuropathic orofacial pain disorders are frequently managed with topical or systemic medications that carry a risk of dangerous side effects such as drowsiness, disorientation, and\/or physical addiction. The aim of this paper is to report the use of neurosensory oral appliances as a safe means of providing symptomatic relief for neuropathic orofacial pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>This is a retrospective chart review of patients with diagnoses of persistent idiopathic facial pain (PIFP), painful post\u2010traumatic trigeminal neuropathy (PTTN), or an oral dysesthesia, who utilized neurosensory appliances with or without the use of topical anesthetic gel.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven patients were identified. Eight patients (62.5%) found benefit with the neurosensory appliance alone, and three patients (37.5%) found relief with the addition of lidocaine 2% gel. All patients reported &gt;50% resolution of their symptoms, with three (37.5%) reporting complete resolution. Seven patients maintained follow\u2010up \u22653\u00a0months, with efficacy lasting for a range of at least 3\u20138\u00a0months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Oral neurosensory appliances, whether used alone as a physical barrier or as a vehicle to deliver topical anesthetic, represent a safe and effective modality for the management of neuropathic orofacial pain disorders. Additional studies are needed to assess long\u2010term efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13824","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T23:59:40Z","timestamp":1614643180000},"page":"805-812","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Oral appliances in the management of neuropathic orofacial pain: A retrospective case series"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8106-7252","authenticated-orcid":false,"given":"Roxanne","family":"Bavarian","sequence":"first","affiliation":[{"name":"Division of Oral Medicine and Dentistry Brigham and Women's Hospital  Boston MA USA"},{"name":"Department of Oral Medicine, Infection, and Immunity Harvard School of Dental Medicine  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shehryar N.","family":"Khawaja","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Shaukat Khanum Memorial Cancer Hospital &amp; Research Centre  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel S.","family":"Treister","sequence":"additional","affiliation":[{"name":"Division of Oral Medicine and Dentistry Brigham and Women's Hospital  Boston MA USA"},{"name":"Department of Oral Medicine, Infection, and Immunity Harvard School of Dental Medicine  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,9]]},"reference":[{"issue":"4","key":"e_1_2_8_2_1","first-page":"165","article-title":"Treatment of smarting symptoms in the oral mucosa by appliance of lingual acrylic splints","volume":"32","author":"Axell T.","year":"2008","journal-title":"Swedish Dental 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