{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T23:07:48Z","timestamp":1782860868323,"version":"3.54.5"},"reference-count":54,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,3,21]],"date-time":"2021-03-21T00:00:00Z","timestamp":1616284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007514","name":"Universit\u00e0 di Pisa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007514","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the prevalence and severity of periodontitis (P) among Italian patients affected by rheumatoid arthritis (RA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      A full\u2010mouth periodontal examination and a rheumatologic\u00a0examination were performed. RA disease activity\u00a0was scored\u00a0using the DAS28. Serum analyses investigated levels of rheumatoid factor, anti\u2010citrullinated\u00a0protein antibodies\u00a0(ACPAs), C\u2010reactive protein, erythrocyte sedimentation rate and fibrinogen. Information concerning smoking, body mass index and RA medical therapy was collected. Data were analysed by Student's\n                      <jats:italic>t<\/jats:italic>\n                      test, chi\u2010square test, binary logistic regression and Spearman's rank.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      This cross\u2010sectional study included 120 subjects, 77 had both diseases while 43 only had RA. The number of teeth present was statistically lower in the RA\u2010P compared to the RA group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). There were statistically more subjects seropositive for ACPAs in the\u00a0RA\u2010P\u00a0group (62.3% vs. 32.6%,\u00a0\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.05). RA\u2010P patients had\u00a0an adjusted OR\u00a0=\u00a02.9 of presenting a moderate\u2010severe DAS28 score (DAS28\u00a0\u2265\u00a03.2).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Higher prevalence of severe\u00a0P was noted among RA subjects. The clinical severity of RA was strongly correlated with the clinical periodontal parameters, and RA subjects also\u00a0affected by P\u00a0had an OR of 2.9 for presenting with a moderate\u2010severe RA (DAS28 score\u00a0\u2265\u00a03.2).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13842","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T13:32:46Z","timestamp":1615383166000},"page":"1715-1722","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Periodontitis in Italian patients with established rheumatoid arthritis: A cross\u2010sectional study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8735-0892","authenticated-orcid":false,"given":"Dimitra","family":"Karapetsa","sequence":"first","affiliation":[{"name":"Section of Dentistry Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Consensi","sequence":"additional","affiliation":[{"name":"Rheumatology Unit Department of Clinical and Experimental Medicine University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Castagnoli","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3849-4304","authenticated-orcid":false,"given":"Morena","family":"Petrini","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa  Pisa Italy"},{"name":"Department of Medical, Oral and Biotechnological Science University G. D\u2019Annunzio of Chieti  Chieti Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Tonelli","sequence":"additional","affiliation":[{"name":"Section of Dentistry Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Gennai","sequence":"additional","affiliation":[{"name":"Section of Dentistry Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Bazzichi","sequence":"additional","affiliation":[{"name":"Rheumatology Unit Department of Clinical and Experimental Medicine University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8780-7306","authenticated-orcid":false,"given":"Filippo","family":"Graziani","sequence":"additional","affiliation":[{"name":"Section of Dentistry Department of Surgical, Medical, Molecular and Critical Area Pathology University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,21]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J.","year":"1975","journal-title":"International Dental Journal"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27584"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/259074"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2751"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600\u2010051X.1999.260203.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37835"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10623"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529\u20100131(200110)45:5<462:AID\u2010ART366>3.0.CO;2\u2010V"},{"issue":"1","key":"e_1_2_9_10_1","first-page":"70","article-title":"Association of periodontal disease and tooth loss with rheumatoid arthritis in the US population","volume":"35","author":"Pablo P.","year":"2008","journal-title":"The Journal of Rheumatology"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.150088"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_398_20"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090309"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.37.4.382"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512457373"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.110664"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092\u20108674(00)81109\u20105"},{"key":"e_1_2_9_18_1","first-page":"29","article-title":"The effect of antirheumatic drugs on circulating immune complexes in rheumatoid arthritis","volume":"58","author":"Forster P.","year":"1986","journal-title":"QJM: An International Journal of Medicine"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11407"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075\u2010020\u20102121\u20106"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2010.01585.x"},{"key":"e_1_2_9_22_1","first-page":"1650","article-title":"Adult periodontitis as a model for rheumatoid arthritis with emphasis on treatment strategies","volume":"26","author":"Greenwald R. 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