{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:18:19Z","timestamp":1787015899217,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T00:00:00Z","timestamp":1620604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate treatment outcomes in patients with severe maxillofacial infections requiring hospital care during a 17\u2010year period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study reviewed 5,465 medical records, and the following data were collected: the reason for infection, locations of inflamed regions, treatment provided, bacteriological findings, and treatment outcomes. Other information included sociodemographic characteristics (age, gender), presence of systemic diseases, and smoking history.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The annual incidence rate of patients with acute maxillofacial infections was 206\u00a0\u00b1\u00a019 cases with a male to female ratio 1.4:1.0, a mean hospital stay of 7.9\u00a0\u00b1\u00a04.9\u00a0days. Older age (&gt;65\u00a0years), smoking and systemic diseases (diabetes), the causative tooth (molar), and need for extraoral incision predicted longer hospitalization. Intravenous penicillin was the most common drug prescribed in 50.5% of cases. A total of 132 different microorganisms were identified. The highest microorganism resistance occurred for metronidazole and the highest sensitivity was to clindamycin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Increased age, smoking, diabetes, causative tooth, and the occurrence of several infected spaces were associated with a longer hospital stay.\n                      <jats:italic>Streptococcus<\/jats:italic>\n                      \u03b1\n                      <jats:italic>haemolyticus<\/jats:italic>\n                      was the most common microorganism found in more than 70.0% of cases that were sensitive to intravenous penicillin.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13894","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T13:11:01Z","timestamp":1619701861000},"page":"1979-1986","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Predictors of longer hospitalization of maxillofacial infections\u2010a 17\u2010year retrospective study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8203-130X","authenticated-orcid":false,"given":"Ruta","family":"Rasteniene","sequence":"first","affiliation":[{"name":"Institute of Odontology Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milda","family":"Vitosyte","sequence":"additional","affiliation":[{"name":"Institute of Odontology Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dainora","family":"Jankauskaite","sequence":"additional","affiliation":[{"name":"Institute of Odontology Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Aleksejuniene","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry University of British Columbia  Vancouver BC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2010.01.019"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.54894"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0975\u20105950.183867"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2018.04.006"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"39","article-title":"Management of complex multi\u2010space odontogenic infections","volume":"82","author":"Bratton T. 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