{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T02:14:22Z","timestamp":1792462462774,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T00:00:00Z","timestamp":1620604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>In this study, we aimed to determine the relationship between oral health status and thyroid dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A population\u2010based cross\u2010sectional analysis using data from the Korean National Health and Nutrition Examination Survey (KNHNES) was performed. We investigated the association between oral health\u2010related parameters and the prevalence of thyroid diseases. In addition, the relationship between oral health status and thyroid function test (TFT) results was analyzed. One\u2010way analysis of variances or chi\u2010square test was used for comparisons between oral health\u2010related parameters and presence of thyroid diseases. Univariable and multivariable logistic regression analyses were conducted to evaluate the associations between participants\u2019 characteristics including oral health\u2010related parameters and the abnormal results of TFTs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 18,034 adults were surveyed. Histories of thyroid diseases were found to be more common in people who brushed their teeth frequently or used oral hygiene products. However, histories of periodontitis and community periodontal index (CPI) did not show significant associations with histories of thyroid diseases. Among 14,860 participants without history of thyroid disorders, people having higher CPI values demonstrated higher probabilities of abnormal TFTs (OR 1.381, 95% CI 1.241\u20121.537,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.0001); however, statistical significance was not found after adjusting for the other variables.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study demonstrated that good oral health\u2010related behavior was associated with more frequent thyroid disease history. High CPI showed a significant association with TFT abnormalities; however, the significance of this association became lower when other variables such as age and sex were adjusted. Further studies will be needed to determine how the control of oral health\u2010related conditions actually has a causal relationship with thyroid disease\/dysfunction through prospective cohort studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13895","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T15:00:21Z","timestamp":1619794821000},"page":"2277-2284","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Association between oral health and thyroid disorders: A population\u2010based cross\u2010sectional study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0772-0708","authenticated-orcid":false,"given":"Minsu","family":"Kwon","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Korea University Anam Hospital Korea University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Jin","family":"Jeong","sequence":"additional","affiliation":[{"name":"Biostatistics Korea University Anam Hospital Korea University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiwon","family":"Kwak","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Korea University Anam Hospital Korea University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang\u2010Yoon","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Korea University Anam Hospital Korea University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung\u2010Kuk","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Korea University Anam Hospital Korea University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf03347442"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2018\u201000163"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.5161"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje\u201012\u20100356"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2018.05.102"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416\u2010018\u20100224\u20105"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-103"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743\u2010422x\u20106\u20105"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201049540\u2010z"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jper.17\u20100575"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0202258"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2147\/jir.S265856"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jper.18\u20100290"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.15384\/kjhp.2020.20.1.10"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010013\u20101112\u20102"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/ccd.ccd_574_18"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020\u2010014\u20100496\u20103"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyt228"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20061414"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2017.32.10.1626"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030\u20106665(20)32302\u20101"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/hypertensionaha.118.11528"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2002.0299"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2018.18"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/105072502753451995"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2018\u201000481"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/6309238"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.01.146"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.13895","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/odi.13895","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.13895","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T23:02:38Z","timestamp":1692572558000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.13895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,10]]},"references-count":28,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1111\/odi.13895"],"URL":"https:\/\/doi.org\/10.1111\/odi.13895","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/ODI.13895\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.13895\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.13895\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.13895\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.13895\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.13895\/v1\/review3","asserted-by":"object"}]},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,10]]},"assertion":[{"value":"2021-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}