{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:53:47Z","timestamp":1772160827510,"version":"3.50.1"},"reference-count":55,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T00:00:00Z","timestamp":1622419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The development of a successful vaccine against severe acute respiratory syndrome coronavirus\u20102 (SARS\u2010CoV\u20102), the agent of coronavirus disease 2019 (COVID\u201019), in an unmatched period of ten months, is a tribute to human ingenuity in the face of a vicious pandemic. A return to pre\u2010pandemic \u201cnormalcy\u201d depends on the successful delivery of the vaccine to a majority (~70%) so as to develop herd immunity critical to arrest the community spread of infection. Vaccination against COVID\u201019 is particularly important for dentistry as the dental team works in an environment replete with aerosol\u2010generating procedures (AGP) that facilitate virus spread. Hence, a COVID\u201019 vaccine is likely to be an obligatory requirement for the dental practice, and the latest addition to the extensive list of vaccines required for dental professionals for the safe delivery of dental care. Here, we review the currently available major candidate vaccines against SARS\u2010CoV\u20102 and their benefits and risks. These include the vaccines developed on next\u2010generation platforms (mRNA, DNA, and viral vector vaccines), and the classic platforms (the live\u2010attenuated virus, and the protein subunit vaccines) The review concludes with a summary of impending issues and challenges facing the provision of COVID\u201019 vaccines for all stakeholders in dentistry.<\/jats:p>","DOI":"10.1111\/odi.13916","type":"journal-article","created":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T11:16:59Z","timestamp":1621077419000},"page":"2326-2336","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Coronavirus disease 2019 (COVID\u201019) vaccines: A concise review"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9122-336X","authenticated-orcid":false,"given":"Lakshman Perera","family":"Samaranayake","sequence":"first","affiliation":[{"name":"Faculty of Dentistry The University of Hong Kong  Hong Kong China (SAR)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0816-538X","authenticated-orcid":false,"given":"Chaminda Jayampath","family":"Seneviratne","sequence":"additional","affiliation":[{"name":"National Dental Research Institute Singapore (NDRIS) Duke NUS Medical School  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0135-6597","authenticated-orcid":false,"given":"Kausar Sadia","family":"Fakhruddin","sequence":"additional","affiliation":[{"name":"Department of Preventive and Restorative Dentistry College of Dental Medicine University of Sharjah  Sharjah UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Summary of infection prevention practices in dental settings","author":"CDC","year":"2020"},{"key":"e_1_2_9_3_1","volume-title":"About COVID\u201019 Vaccination. 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