{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T23:14:10Z","timestamp":1783120450333,"version":"3.54.6"},"reference-count":60,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To undertake a meta\u2010analysis of the association of Oral Lichen Planus (OLP) with diabetes, two diseases with an important impact on public health and the economy, but the evidence of which about their association is inconsistent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Relevant studies were localized by searching MEDLINE, EMBASE, Conference Proceedings, and other databases from inception to October 2020, without restrictions. The reference lists of included studies and of related reviews were also inspected. Global pooled odds ratios were calculated, and predefined subgroup analyses were performed. The heterogeneity between studies and publication bias was assessed and sensitivity analysis was carried out.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010two studies were included in the meta\u2010analysis. Pooled ORs showed a moderate association between diabetes and OLP [OR: 1.87 (95%CI: 1.57, 2.34)]. The association is limited to studies carried out on adults only [OR: 2.12 (95%CI: 1.75, 2.57)] and is observed in all study designs. Globally, the heterogeneity was low to moderate. Studies carried out in European populations show a stronger association of diabetes and OLP than Asiatic studies [OR: 2.49 (95%CI: 1.87, 3.32) and 1.60 (95%CI: 1.25, 2.03), respectively].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Diabetes and OLP are moderately associated. Systematic diagnosis of diabetes in OLP patients could prove useful.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.13927","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T18:57:16Z","timestamp":1622746636000},"page":"2100-2109","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Diabetes mellitus and oral lichen planus: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"28","author":[{"given":"Narmeen","family":"Mallah","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBER\u2010ESP)  Madrid Spain"},{"name":"Health Research Institute of Santiago de Compostela (IDIS)  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7911-5190","authenticated-orcid":false,"given":"Pablo","family":"Ignacio Varela\u2010Centelles","sequence":"additional","affiliation":[{"name":"Health Research Institute of Santiago de Compostela (IDIS)  Santiago de Compostela Spain"},{"name":"Praza de Ferrol Health Center Galician Health Service  Lugo Spain"},{"name":"Department of Surgery and Medical\u2010Surgical Specialties School of Medicine and Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Seoane\u2010Romero","sequence":"additional","affiliation":[{"name":"Rheumatology Department General University Hospital  Ciudad Real Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0739-2241","authenticated-orcid":false,"given":"Bahi","family":"Takkouche","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBER\u2010ESP)  Madrid Spain"},{"name":"Health Research Institute of Santiago de Compostela (IDIS)  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100714.2007.00581.x"},{"issue":"4","key":"e_1_2_8_3_1","first-page":"39","article-title":"Prevalence of oral mucosal lesions in patients with type 2 diabetes attending Hospital Universiti Sains Malaysia","volume":"20","author":"Al\u2010Maweri S. 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