{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T11:12:17Z","timestamp":1772709137757,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T00:00:00Z","timestamp":1626220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Recurrent aphthous stomatitis (RAS) is a condition that affects 20% of the world population and is characterized by painful ulcers in the oral mucosa. So far, the epidemiology and risk factors of RAS have been infrequently studied. Our objective was to determine whether sleep\u2010related factors are related to the occurrence of RAS in the first prospective study carried out on this topic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cohort of 11210 Spanish students, 13\u201317\u00a0years old, was followed up for one year. Sleep disorders were assessed at baseline using a standard validated questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We detected 2655 new cases of RAS with a total of 287,262 person\u2010week of follow\u2010up. Subjects with high (4th quartile) Insomnia Index showed an incidence rate ratio (IRR) of RAS of 1.29 (95% confidence interval (CI) 1.15\u20131.45), while subjects with high Hypersomnia Index presented an IRR of 1.42 (95% CI 1.26\u20131.61). A high score of sleep\u2010related phenomena was also associated with an increased IRR: 1.53 (95% CI 1.37\u20131.69). Adolescents with high level of sleep satisfaction were at lower risk of RAS: 0.88 (95% CI 0.77\u20131.01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings suggest that sleep disorders are moderately associated with RAS in adolescents.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.13955","type":"journal-article","created":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T13:00:05Z","timestamp":1625835605000},"page":"1882-1890","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Sleep quality and risk of recurrent aphthous ulcers: A Spanish cohort study"],"prefix":"10.1111","volume":"28","author":[{"given":"Hamid Reza","family":"Tohidinik","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"HIV\/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance Institute for Futures Studies in Health Kerman University of Medical Sciences  Kerman Iran"},{"name":"Department of Epidemiology and Biostatistics School of Public Health Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almudena","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Regueira\u2010M\u00e9ndez","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBER\u2010ESP  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0739-2241","authenticated-orcid":false,"given":"Bahi","family":"Takkouche","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica (CIBER\u2010ESP  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2013.12.002"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.214.291"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13052\u2010017\u20100367\u20107"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp\u2010journals\u201010024\u20101117"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389450116666150518095650"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/10253890.2015.1087503"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1992.01820080059010"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006\u20103223(95)00188\u20103"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0733\u20108635(02)00064\u20105"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1807\u201059322009000700007"},{"key":"e_1_2_10_12_1","first-page":"107","article-title":"Propiedades psicom\u00e9tricas del cuestionario Oviedo de sue\u00f1o","volume":"12","author":"Garc\u00eda J. 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